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    Obesity, health-care utilization, and health-related quality of life after fracture in postmenopausal women: Global Longitudinal Study of Osteoporosis in Women (GLOW)

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    Authors
    Compston, Juliet E.
    Flahive, Julie
    Hooven, Fred H.
    Anderson, Frederick A. Jr.
    Gehlbach, Stephen H.
    Boonen, Steven
    UMass Chan Affiliations
    Center for Outcomes Research
    Document Type
    Journal Article
    Publication Date
    2014-02-01
    Keywords
    Aged; Aged, 80 and over; Body Mass Index; Female; Health Resources; Health Status; Humans; Length of Stay; Longitudinal Studies; Middle Aged; Obesity; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Quality of Life; Surveys and Questionnaires
    Health Services Research
    Musculoskeletal Diseases
    Women's Health
    
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    Link to Full Text
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917823/
    Abstract
    Fractures may be associated with higher morbidity in obese postmenopausal women than in nonobese women. We compared health-care utilization, functional status, and health-related quality of life (HRQL) in obese, nonobese, and underweight women with fractures. Information from the GLOW study, started in 2006, was collected at baseline and at 1, 2, and 3 years. In this subanalysis, self-reported incident clinical fractures, health-care utilization, HRQL, and functional status were recorded and examined. Women in GLOW (n = 60,393) were aged ≥55 years, from 723 physician practices at 17 sites in 10 countries. Complete data for fracture and body mass index were available for 90 underweight, 3,270 nonobese, and 941 obese women with one or more incident clinical fractures during the 3-year follow-up. The median hospital length of stay, adjusted for age, comorbidities, and fracture type, was significantly greater in obese than nonobese women (6 vs. 5 days, p = 0.017). Physical function and vitality score were significantly worse in obese than in nonobese women, both before and after fracture; but changes after fracture were similar across groups. Use of antiosteoporosis medication was significantly lower in obese than in nonobese or underweight women. In conclusion, obese women with fracture undergo a longer period of hospitalization for treatment and have poorer functional status and HRQL than nonobese women. Whether these differences translate into higher economic costs and adverse effects on longer-term outcomes remains to be established.
    Source

    Calcif Tissue Int. 2014 Feb;94(2):223-31. Link to article on publisher's website

    DOI
    10.1007/s00223-013-9801-z
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/27161
    PubMed ID
    24077896
    Notes

    Full author list omitted for brevity. For the full list of authors, see article.

    Related Resources

    Link to article in PubMed

    ae974a485f413a2113503eed53cd6c53
    10.1007/s00223-013-9801-z
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