• Login
    View Item 
    •   Home
    • UMass Chan Departments, Programs and Centers
    • Center for Outcomes Research
    • IMPROVE Publications
    • View Item
    •   Home
    • UMass Chan Departments, Programs and Centers
    • Center for Outcomes Research
    • IMPROVE Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of eScholarship@UMassChanCommunitiesPublication DateAuthorsUMass Chan AffiliationsTitlesDocument TypesKeywordsThis CollectionPublication DateAuthorsUMass Chan AffiliationsTitlesDocument TypesKeywords

    My Account

    LoginRegister

    Help

    AboutSubmission GuidelinesData Deposit PolicySearchingAccessibilityTerms of UseWebsite Migration FAQ

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Venous thromboembolism prophylaxis in acutely ill hospitalized medical patients: findings from the International Medical Prevention Registry on Venous Thromboembolism

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Tapson, Victor F.
    Decousus, Herve
    Pini, Mario
    Chong, Beng H.
    Froehlich, James B.
    Monreal, Manuel
    Spyropoulos, Alex C.
    Merli, Geno J.
    Zotz, Rainer B.
    Bergmann, Jean-Francois
    Pavanello, Ricardo
    Turpie, Alexander G. G.
    Nakamura, Mashio
    Piovella, Franco
    Kakkar, Ajay K.
    Spencer, Frederick A.
    Fitzgerald, Gordon
    Anderson, Frederick A. Jr.
    IMPROVE Investigators
    Show allShow less
    UMass Chan Affiliations
    Department of Medicine, Division of Cardiovascular Medicine
    Center for Outcomes Research
    Document Type
    Journal Article
    Publication Date
    2007-09-19
    Keywords
    Acute Disease
    Aged
    Anticoagulants
    Female
    Fibrinolytic Agents
    Hospitalization
    Humans
    Intermittent Pneumatic Compression Devices
    Male
    Middle Aged
    Physician's Practice Patterns
    *Registries
    Risk Factors
    Thromboembolism
    Venous Thrombosis
    Cardiovascular Diseases
    Health Services Research
    Show allShow less
    
    Metadata
    Show full item record
    Link to Full Text
    http://dx.doi.org/10.1378/chest.06-2993
    Abstract
    BACKGROUND: Evidence-based guidelines recommend that acutely ill hospitalized medical patients who are at risk of venous thromboembolism (VTE) should receive prophylaxis. Our aim was to characterize the clinical practices for VTE prophylaxis in acutely ill hospitalized medical patients enrolled in the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE). METHODS: IMPROVE is an ongoing, multinational, observational study. Participating hospitals enroll the first 10 consecutive eligible acutely ill medical patients each month. Patient management is determined by the treating physicians. An analysis of data on VTE prophylaxis practices is presented. RESULTS: From July 2002 to September 30, 2006, 15,156 patients were enrolled from 52 hospitals in 12 countries, of whom 50% received in-hospital pharmacologic and/or mechanical VTE prophylaxis. In the United States and other participating countries, 52% and 43% of patients, respectively, should have received prophylaxis according to guideline recommendations from the American College of Chest Physicians (ACCP). Only approximately 60% of patients who either met the ACCP criteria for requiring prophylaxis or were eligible for enrollment in randomized clinical trials that have shown the benefits of pharmacologic prophylaxis actually received prophylaxis. Practices varied considerably. Intermittent pneumatic compression was the most common form of medical prophylaxis utilized in the United States, although it was used very rarely in other countries (22% vs 0.2%, respectively). Unfractionated heparin was the most frequent pharmacologic approach used in the United States (21% of patients), with low-molecular-weight heparin used most frequently in other participating countries (40%). There was also variable use of elastic stockings in the United States and other participating countries (3% vs 7%, respectively). CONCLUSIONS: Our data suggest that physicians' practices for providing VTE prophylaxis to acutely ill hospitalized medical patients are suboptimal and highlight the need for improved implementation of existing evidence-based guidelines in hospitals.
    Source
    Chest. 2007 Sep;132(3):936-45. Epub 2007 Jun 15. Link to article on publisher's site
    DOI
    10.1378/chest.06-2993
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/27301
    PubMed ID
    17573514
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1378/chest.06-2993
    Scopus Count
    Collections
    IMPROVE Publications

    entitlement

    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Lamar Soutter Library, UMass Chan Medical School | 55 Lake Avenue North | Worcester, MA 01655 USA
    Quick Guide | escholarship@umassmed.edu
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.