SARS-CoV-2 and nervous system: From pathogenesis to clinical manifestation
Umeton, Raffaella Pizzolato
UMass Chan AffiliationsDepartment of Neurology
KeywordsCoronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Immunology of Infectious Disease
Nervous System Diseases
Neuroscience and Neurobiology
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AbstractSince the coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a growing body of evidence indicates that besides common COVID-19 symptoms, patients may develop various neurological manifestations affecting both the central and peripheral nervous systems as well as skeletal muscles. These manifestations can occur prior, during and even after the onset of COVID-19 general symptoms. In this Review, we discuss the possible neuroimmunological mechanisms underlying the nervous system and skeletal muscle involvement, and viral triggered neuroimmunological conditions associated with SARS-CoV-2, as well as therapeutic approaches that have been considered for these specific complications worldwide.
Keyhanian K, Umeton RP, Mohit B, Davoudi V, Hajighasemi F, Ghasemi M. SARS-CoV-2 and nervous system: From pathogenesis to clinical manifestation. J Neuroimmunol. 2020 Nov 7;350:577436. doi: 10.1016/j.jneuroim.2020.577436. Epub ahead of print. PMID: 33212316; PMCID: PMC7647896. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/27357
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