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    A COVID clash: How to proceed when IACUCs and IBCs disagree

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    Authors
    Silverman, Jerald
    UMass Chan Affiliations
    Department of Pathology
    Document Type
    Journal Article
    Publication Date
    2021-01-01
    Keywords
    Animal Experimentation and Research
    Veterinary Medicine
    
    Metadata
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    Link to Full Text
    https://doi.org/10.1038/s41684-020-00686-8
    Abstract
    Mayfield proposed to perform his mouse experiments at the ABSL-3 level and keep the SARS-CoV-2 coronavirus under BSL-3 conditions. But although Mayfield had proper past experience working under BSL-3 and ABSL-3 conditions, Great Eastern did not have BSL-3 or ABSL-3 facilities. Mayfield was well aware of this problem and with the knowledge of the school’s IACUC and Institutional Biosafety Committee (IBC) chairpersons, he had submitted IACUC and IBC applications to a nearby contract research organization (CRO) that had the needed biocontainment facilities and would allow Mayfield to use those facilities. Both of those applications had been approved by the CRO and now, following Great Eastern policy, the same approved applications were submitted for concurrence by the IBC and IACUC of Great Eastern University. The IACUC voted to agree with the CRO’s approval, but the IBC did not, citing inadequate containment if a mouse were to escape from its cage while at the CRO. The result was a de facto halt to the planned experiments.
    Source

    Silverman J. A COVID clash: How to proceed when IACUCs and IBCs disagree? Lab Anim (NY). 2021 Jan;50(1):3. doi: 10.1038/s41684-020-00686-8. PMID: 33339993. Link to article on publisher's site

    DOI
    10.1038/s41684-020-00686-8
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/27410
    PubMed ID
    33339993
    Related Resources

    Link to Article in PubMed

    ae974a485f413a2113503eed53cd6c53
    10.1038/s41684-020-00686-8
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