SARS-CoV-2 Reinfection in a Liver Transplant Recipient

Authors
Tomkins-Tinch, Christopher H.
Daly, Jennifer S.
Theodoropoulos, Nicole M.
Madaio, Michael P.
Yu, Neng
Vanguri, Vijay K.
Movahedi, Babak
Bozorgzadeh, Adel
Simin, Karl J.
Luban, Jeremy
UMass Chan Affiliations
Program in Molecular Medicine
Department of Molecular, Cell and Cancer Biology
Department of Surgery
Department of Pathology, Division of Anatomic Pathology
Department of Medicine, Division of Infectious Diseases and Immunology
Document Type
Journal Article
Publication Date
2021-04-20
Keywords
liver transplants
SARS-CoV-2 infection
COVID-19
reinfection
Hepatology
Immunology and Infectious Disease
Infectious Disease
Microbiology
Pathology
Surgery

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Link to Full Text
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059415/
Abstract
We present a case of a liver transplant recipient with 2 distinct SARS-CoV-2 infections, separated by 111 days without symptoms and 2 negative test results for SARS-CoV-2 infection. The clinical course suggested reinfection, and viral genomic sequencing was used to distinguish whether the later positive samples were due to SARS-CoV-2 relapse or reinfection.
Source

Tomkins-Tinch CH, Daly JS, Gladden-Young A, Theodoropoulos NM, Madaio MP, Yu N, Vanguri VK, Siddle KJ, Adams G, Krasilnikova LA, Movahedi B, Bozorgzadeh A, Simin K, Lemieux JE, Luban J, Park DJ, MacInnis BL, Sabeti PC, Levitz SM. SARS-CoV-2 Reinfection in a Liver Transplant Recipient. Ann Intern Med. 2021 Apr 20:L21-0108. doi: 10.7326/L21-0108. Epub ahead of print. PMID: 33872044; PMCID: PMC8059415. Link to article on publisher's site
DOI
10.7326/L21-0108
Permanent Link to this Item
http://hdl.handle.net/20.500.14038/27430
PubMed ID
33872044
Notes

Full author list omitted for brevity. For the full list of authors, see article.
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