Antibodies, boosters and optimizing SARS-CoV-2 vaccine for transplantation: A call for more research
AuthorsIson, Michael G.
Theodoropoulos, Nicole M.
Wolfe, Cameron R.
UMass Chan AffiliationsDepartment of Medicine, Division of Infectious Diseases and Immunology
Document TypeAccepted Manuscript
Immunology of Infectious Disease
Immunoprophylaxis and Therapy
Surgical Procedures, Operative
MetadataShow full item record
AbstractDespite emerging data suggesting reduced antibody responses among SOT recipients following SARS-CoV-2 vaccine, critical unanswered questions remain. The clinical implications of the reduced humoral response need to be assessed through prospective studies. Studies are likewise needed to inform which vaccine dosing strategies result in improved immunity and if such approaches maximize protection against severe infection in the vulnerable transplant population.
Ison MG, Blumberg E, Halasa N, Kaul D, Theodoropoulos NM, Wolfe CR. Antibodies, boosters and optimizing SARS-CoV-2 vaccine for transplantation: A call for more research. Am J Transplant. 2021 Jul 9. doi: 10.1111/ajt.16758. Epub ahead of print. PMID: 34241964. Link to article on publisher's site