Antibodies, boosters and optimizing SARS-CoV-2 vaccine for transplantation: A call for more research
Authors
Ison, Michael G.Blumberg, Emily
Halasa, Natasha
Kaul, Dan
Theodoropoulos, Nicole M.
Wolfe, Cameron R.
UMass Chan Affiliations
Department of Medicine, Division of Infectious Diseases and ImmunologyDocument Type
Accepted ManuscriptPublication Date
2021-07-09Keywords
SARS-CoV-2COVID-19
vaccine
antibodies
antibody response
Immunology of Infectious Disease
Immunoprophylaxis and Therapy
Immunotherapy
Infectious Disease
Microbiology
Surgical Procedures, Operative
Virus Diseases
Metadata
Show full item recordAbstract
Despite emerging data suggesting reduced antibody responses among SOT recipients following SARS-CoV-2 vaccine, critical unanswered questions remain. The clinical implications of the reduced humoral response need to be assessed through prospective studies. Studies are likewise needed to inform which vaccine dosing strategies result in improved immunity and if such approaches maximize protection against severe infection in the vulnerable transplant population.Source
Ison MG, Blumberg E, Halasa N, Kaul D, Theodoropoulos NM, Wolfe CR. Antibodies, boosters and optimizing SARS-CoV-2 vaccine for transplantation: A call for more research. Am J Transplant. 2021 Jul 9. doi: 10.1111/ajt.16758. Epub ahead of print. PMID: 34241964. Link to article on publisher's site
DOI
10.1111/ajt.16758Permanent Link to this Item
http://hdl.handle.net/20.500.14038/27456PubMed ID
34241964Related Resources
Rights
This article is protected by copyright. All rights reserved. This is a PDF file of an accepted manuscript that has been accepted for publication and posted with a 12-month embargo as allowed by the publisher’s author rights policy at https://authorservices.wiley.com/author-resources/Journal-Authors/licensing/self-archiving.html. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.ae974a485f413a2113503eed53cd6c53
10.1111/ajt.16758