Advancing Stage of Female Reproductive Life Associated with Bipolar Illness Exacerbation
dc.contributor.author | Marsh, Wendy K. | |
dc.contributor.author | Ketter, Terence | |
dc.contributor.author | Crawford, Sybil L. | |
dc.contributor.author | Johnson, Julia V. | |
dc.contributor.author | Rothschild, Anthony J. | |
dc.date | 2022-08-11T08:08:12.000 | |
dc.date.accessioned | 2022-08-23T15:46:12Z | |
dc.date.available | 2022-08-23T15:46:12Z | |
dc.date.issued | 2011-05-20 | |
dc.date.submitted | 2011-08-05 | |
dc.identifier.doi | 10.13028/2jk9-pr80 | |
dc.identifier.uri | http://hdl.handle.net/20.500.14038/27700 | |
dc.description.abstract | Introduction: Perimenopause confers an increased risk of depression in the general population, yet bipolar disorder mood course remains unknown. Methods: Clinic visits in 519 premenopausal, 116 perimenopausal including 13 women transitioning from peri- to postmenopause, and 133 postmenopausal women with bipolar disorder who received naturalistic treatment in the multisite STEP-Bipolar Disorder study over 19.8 +/- 15.5 months were analyzed for mood state. Results: Advancing female reproductive stage was associated with significant decline in mood elevation; significant decline in euthymia; no significant difference in major depression; and symptomatic significant increase. Conclusions: Advancing stage of female reproductive life was associated with bipolar illness exacerbation. Women transitioning from peri- to postmenopause had significantly greater depression than other female reproductive groups. | |
dc.format | youtube | |
dc.language.iso | en_US | |
dc.rights | Copyright the Author(s) | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | |
dc.subject | Maternal and Child Health | |
dc.subject | Obstetrics and Gynecology | |
dc.subject | Psychiatry | |
dc.subject | Psychiatry and Psychology | |
dc.title | Advancing Stage of Female Reproductive Life Associated with Bipolar Illness Exacerbation | |
dc.type | Poster | |
dc.identifier.legacyfulltext | https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1011&context=cts_retreat&unstamped=1 | |
dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/cts_retreat/2011/posters/7 | |
dc.identifier.contextkey | 2134926 | |
refterms.dateFOA | 2022-08-23T15:46:12Z | |
html.description.abstract | <p><strong>Introduction: </strong>Perimenopause confers an increased risk of depression in the general population, yet bipolar disorder mood course remains unknown.</p> <p><strong>Methods:</strong> Clinic visits in 519 premenopausal, 116 perimenopausal including 13 women transitioning from peri- to postmenopause, and 133 postmenopausal women with bipolar disorder who received naturalistic treatment in the multisite STEP-Bipolar Disorder study over 19.8 +/- 15.5 months were analyzed for mood state.</p> <p><strong>Results: </strong>Advancing female reproductive stage was associated with significant decline in mood elevation; significant decline in euthymia; no significant difference in major depression; and symptomatic significant increase.</p> <p><strong>Conclusions: </strong>Advancing stage of female reproductive life was associated with bipolar illness exacerbation. Women transitioning from peri- to postmenopause had significantly greater depression than other female reproductive groups.</p> | |
dc.identifier.submissionpath | cts_retreat/2011/posters/7 |