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dc.contributor.authorMarsh, Wendy K.
dc.contributor.authorKetter, Terence
dc.contributor.authorCrawford, Sybil L.
dc.contributor.authorJohnson, Julia V.
dc.contributor.authorRothschild, Anthony J.
dc.date2022-08-11T08:08:12.000
dc.date.accessioned2022-08-23T15:46:12Z
dc.date.available2022-08-23T15:46:12Z
dc.date.issued2011-05-20
dc.date.submitted2011-08-05
dc.identifier.doi10.13028/2jk9-pr80
dc.identifier.urihttp://hdl.handle.net/20.500.14038/27700
dc.description.abstractIntroduction: Perimenopause confers an increased risk of depression in the general population, yet bipolar disorder mood course remains unknown. Methods: Clinic visits in 519 premenopausal, 116 perimenopausal including 13 women transitioning from peri- to postmenopause, and 133 postmenopausal women with bipolar disorder who received naturalistic treatment in the multisite STEP-Bipolar Disorder study over 19.8 +/- 15.5 months were analyzed for mood state. Results: Advancing female reproductive stage was associated with significant decline in mood elevation; significant decline in euthymia; no significant difference in major depression; and symptomatic significant increase. Conclusions: Advancing stage of female reproductive life was associated with bipolar illness exacerbation. Women transitioning from peri- to postmenopause had significantly greater depression than other female reproductive groups.
dc.formatyoutube
dc.language.isoen_US
dc.rightsCopyright the Author(s)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/
dc.subjectMaternal and Child Health
dc.subjectObstetrics and Gynecology
dc.subjectPsychiatry
dc.subjectPsychiatry and Psychology
dc.titleAdvancing Stage of Female Reproductive Life Associated with Bipolar Illness Exacerbation
dc.typePoster
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1011&context=cts_retreat&unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/cts_retreat/2011/posters/7
dc.identifier.contextkey2134926
refterms.dateFOA2022-08-23T15:46:12Z
html.description.abstract<p><strong>Introduction: </strong>Perimenopause confers an increased risk of depression in the general population, yet bipolar disorder mood course remains unknown.</p> <p><strong>Methods:</strong> Clinic visits in 519 premenopausal, 116 perimenopausal including 13 women transitioning from peri- to postmenopause, and 133 postmenopausal women with bipolar disorder who received naturalistic treatment in the multisite STEP-Bipolar Disorder study over 19.8 +/- 15.5 months were analyzed for mood state.</p> <p><strong>Results: </strong>Advancing female reproductive stage was associated with significant decline in mood elevation; significant decline in euthymia; no significant difference in major depression; and symptomatic significant increase.</p> <p><strong>Conclusions: </strong>Advancing stage of female reproductive life was associated with bipolar illness exacerbation. Women transitioning from peri- to postmenopause had significantly greater depression than other female reproductive groups.</p>
dc.identifier.submissionpathcts_retreat/2011/posters/7


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