Data from: Lactose Intolerance: Lack of Evidence for Short Stature or Vitamin D Deficiency in Prepubertal Children
Lactose intolerance dataset in ...
Maranda, Louise S.
Fong, Jay G.
Rogol, Alan D.
Nwosu, Benjamin U.
UMass Chan AffiliationsDepartment of Quantitative Health Sciences
Department of Pediatrics
KeywordsVitamin D deficiency
Body Mass Index
Endocrinology, Diabetes, and Metabolism
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AbstractBackground: The health consequences of lactose intolerance (LI) are unclear. Aims: To investigate the effects of LI on stature and vitamin D status. Hypotheses: LI subjects will have similar heights and vitamin D status as controls. Subjects and Methods: Prepubertal children of ages 3-12 years with LI (n=38, age 8.61 ± 3.08y, male/female 19/19) were compared to healthy, age- and gender-matched controls (n=49, age 7.95±2.64, male/female 28/21). Inclusion criteria: prepubertal status (boys: testicular volume Results: There was no significant difference in 25(OH)D between the LI and non-LI subjects (60.1±21.1, vs. 65.4 ± 26.1 nmol/L, p = 0.29). Upon stratification into normal weight (BMI percentile) vs. overweight/obese (BMI ≥85th percentile), the normal weight controls had significantly higher 25(OH)D level than both the normal weight LI children (78.3 ± 32.6 vs. 62.9 ± 23.2, p = 0.025), and the overweight/obese LI children (78.3±32.6 vs. 55.3±16.5, p = 0.004). Secondly, there was no overall difference in height z-score between the LI children and controls. The normal weight LI patients had similar height as normal controls (-0.46 ± 0.89 vs. -0.71 ± 1.67, p = 0.53), while the overweight/obese LI group was taller than the normal weight controls (0.36 ± 1.41 vs. -0.71 ± 1.67, p = 0.049), and of similar height as the overweight/obese controls (0.36 ± 1.41 vs. 0.87 ± 1.45, p = 0.28). MPTH z-score was similar between the groups. Conclusion: Short stature and vitamin D deficiency are not features of LI in prepubertal children.
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/28274
This dataset (.csv file, 11 KB) is the primary data source for the following published study: Setty-Shah N, Maranda L, Candela N, Fong J, Dahod I, et al. (2013) Lactose Intolerance: Lack of Evidence for Short Stature or Vitamin D Deficiency in Prepubertal Children. PLoS ONE 8(10): e78653. doi:10.1371/journal.pone.0078653
RightsCopyright © 2013 The Author(s)