TNFalpha-Mediated Cytotoxic Responses to IAP Inhibition Are Limited by the p38alpha MAPK Pathway
Document TypeJournal Article
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AbstractSmac mimetics (SMs), a class of drugs that can promote tumor cell death, represent a potential therapeutic strategy for the treatment of cancer. In this issue of Cancer Cell, Lalaoui et al. (2016) report that SM efficacy can be potently increased by inhibition of the p38alpha MAPK/MK2 signaling pathway.
SourceCancer Cell. 2016 Feb 8;29(2):131-3. doi: 10.1016/j.ccell.2016.01.008. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/28290
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