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dc.contributor.authorYosipovitch, Gil
dc.contributor.authorBernhard, Jeffrey D.
dc.date2022-08-11T08:08:17.000
dc.date.accessioned2022-08-23T15:49:19Z
dc.date.available2022-08-23T15:49:19Z
dc.date.issued2013-04-25
dc.date.submitted2015-11-13
dc.identifier.citationN Engl J Med. 2013 Apr 25;368(17):1625-34. doi: 10.1056/NEJMcp1208814. <a href="http://dx.doi.org/10.1056/NEJMcp1208814">Link to article on publisher's site</a>
dc.identifier.issn0028-4793 (Linking)
dc.identifier.doi10.1056/NEJMcp1208814
dc.identifier.pmid23614588
dc.identifier.urihttp://hdl.handle.net/20.500.14038/28403
dc.description.abstractThis Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations. Case: An otherwise healthy 55-year-old man reports that he has been itchy all over for 6 months. The itch interferes with falling asleep and wakes him repeatedly during the night. Initially, there was no rash, but during the past 4 months, itchy nodules and plaques have developed on his back, arms, and legs. Treatment with sedating and nonsedating oral antihistamines and topical glucocorticoids has had no effect. How would you evaluate and manage this case?
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=23614588&dopt=Abstract">Link to Article in PubMed</a>
dc.rights<p>Publisher PDF posted as allowed by the publisher's author rights policy at http://www.nejm.org/page/author-center/permissions.</p>
dc.subjectAmines
dc.subjectAntidepressive Agents, Tricyclic
dc.subjectBehavior Therapy
dc.subjectChronic Disease
dc.subjectCyclohexanecarboxylic Acids
dc.subjectEmollients
dc.subjectExcitatory Amino Acid Antagonists
dc.subjectHistamine Antagonists
dc.subjectHumans
dc.subjectMale
dc.subjectMianserin
dc.subjectMiddle Aged
dc.subjectPruritus
dc.subjectgamma-Aminobutyric Acid
dc.subjectDermatology
dc.subjectSkin and Connective Tissue Diseases
dc.titleClinical practice. Chronic pruritus
dc.typeJournal Article
dc.source.journaltitleThe New England journal of medicine
dc.source.volume368
dc.source.issue17
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1080&amp;context=derm_pubs&amp;unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/derm_pubs/75
dc.identifier.contextkey7843024
refterms.dateFOA2022-08-23T15:49:19Z
html.description.abstract<p>This <em>Journal</em> feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations. Case: An otherwise healthy 55-year-old man reports that he has been itchy all over for 6 months. The itch interferes with falling asleep and wakes him repeatedly during the night. Initially, there was no rash, but during the past 4 months, itchy nodules and plaques have developed on his back, arms, and legs. Treatment with sedating and nonsedating oral antihistamines and topical glucocorticoids has had no effect. How would you evaluate and manage this case?</p>
dc.identifier.submissionpathderm_pubs/75
dc.contributor.departmentDepartment of Medicine, Division of Dermatology
dc.source.pages1625-34


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