Clinical practice. Chronic pruritus
dc.contributor.author | Yosipovitch, Gil | |
dc.contributor.author | Bernhard, Jeffrey D. | |
dc.date | 2022-08-11T08:08:17.000 | |
dc.date.accessioned | 2022-08-23T15:49:19Z | |
dc.date.available | 2022-08-23T15:49:19Z | |
dc.date.issued | 2013-04-25 | |
dc.date.submitted | 2015-11-13 | |
dc.identifier.citation | N Engl J Med. 2013 Apr 25;368(17):1625-34. doi: 10.1056/NEJMcp1208814. <a href="http://dx.doi.org/10.1056/NEJMcp1208814">Link to article on publisher's site</a> | |
dc.identifier.issn | 0028-4793 (Linking) | |
dc.identifier.doi | 10.1056/NEJMcp1208814 | |
dc.identifier.pmid | 23614588 | |
dc.identifier.uri | http://hdl.handle.net/20.500.14038/28403 | |
dc.description.abstract | This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations. Case: An otherwise healthy 55-year-old man reports that he has been itchy all over for 6 months. The itch interferes with falling asleep and wakes him repeatedly during the night. Initially, there was no rash, but during the past 4 months, itchy nodules and plaques have developed on his back, arms, and legs. Treatment with sedating and nonsedating oral antihistamines and topical glucocorticoids has had no effect. How would you evaluate and manage this case? | |
dc.language.iso | en_US | |
dc.relation | <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=23614588&dopt=Abstract">Link to Article in PubMed</a> | |
dc.rights | <p>Publisher PDF posted as allowed by the publisher's author rights policy at http://www.nejm.org/page/author-center/permissions.</p> | |
dc.subject | Amines | |
dc.subject | Antidepressive Agents, Tricyclic | |
dc.subject | Behavior Therapy | |
dc.subject | Chronic Disease | |
dc.subject | Cyclohexanecarboxylic Acids | |
dc.subject | Emollients | |
dc.subject | Excitatory Amino Acid Antagonists | |
dc.subject | Histamine Antagonists | |
dc.subject | Humans | |
dc.subject | Male | |
dc.subject | Mianserin | |
dc.subject | Middle Aged | |
dc.subject | Pruritus | |
dc.subject | gamma-Aminobutyric Acid | |
dc.subject | Dermatology | |
dc.subject | Skin and Connective Tissue Diseases | |
dc.title | Clinical practice. Chronic pruritus | |
dc.type | Journal Article | |
dc.source.journaltitle | The New England journal of medicine | |
dc.source.volume | 368 | |
dc.source.issue | 17 | |
dc.identifier.legacyfulltext | https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1080&context=derm_pubs&unstamped=1 | |
dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/derm_pubs/75 | |
dc.identifier.contextkey | 7843024 | |
refterms.dateFOA | 2022-08-23T15:49:19Z | |
html.description.abstract | <p>This <em>Journal</em> feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations. Case: An otherwise healthy 55-year-old man reports that he has been itchy all over for 6 months. The itch interferes with falling asleep and wakes him repeatedly during the night. Initially, there was no rash, but during the past 4 months, itchy nodules and plaques have developed on his back, arms, and legs. Treatment with sedating and nonsedating oral antihistamines and topical glucocorticoids has had no effect. How would you evaluate and manage this case?</p> | |
dc.identifier.submissionpath | derm_pubs/75 | |
dc.contributor.department | Department of Medicine, Division of Dermatology | |
dc.source.pages | 1625-34 |