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dc.contributor.authorMatar, C. G.
dc.contributor.authorJacobs, N. T.
dc.contributor.authorSpeck, S. H.
dc.contributor.authorLamb, T. J.
dc.contributor.authorMoormann, Ann M.
dc.date2022-08-11T08:08:22.000
dc.date.accessioned2022-08-23T15:52:26Z
dc.date.available2022-08-23T15:52:26Z
dc.date.issued2015-09-01
dc.date.submitted2017-06-30
dc.identifier.citation<p>Parasite Immunol. 2015 Sep;37(9):433-45. doi: 10.1111/pim.12212. <a href="https://doi.org/10.1111/pim.12212">Link to article on publisher's site</a></p>
dc.identifier.issn0141-9838 (Linking)
dc.identifier.doi10.1111/pim.12212
dc.identifier.pmid26121587
dc.identifier.urihttp://hdl.handle.net/20.500.14038/29135
dc.description.abstractPlasmodium falciparum infections have been implicated in immune deficiencies resulting in ineffective control of Epstein-Barr virus, thereby increasing the risk of endemic Burkitt lymphoma in children. However, the impact of Epstein-Barr virus infections on the development of immunity to P. falciparum has not been studied in depth. In this review, we examine novel findings from animal co-infection models and human immuno-epidemiologic studies to speculate on the impact of acute gammaherpesvirus co-infection on malarial disease severity. Children are often concurrently or sequentially infected with multiple pathogens, and this has implications for understanding the development of protective immunity as well as in the evaluation of vaccine efficacy.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=26121587&dopt=Abstract">Link to Article in PubMed</a></p>
dc.relation.urlhttps://doi.org/10.1111/pim.12212
dc.subjectanimal models
dc.subjectco‐infection
dc.subjectepidemiologic studies
dc.subjectimmunity
dc.subjectAnimal Experimentation and Research
dc.subjectEpidemiology
dc.subjectHemic and Immune Systems
dc.subjectImmunopathology
dc.subjectParasitic Diseases
dc.subjectParasitology
dc.subjectPathology
dc.subjectViruses
dc.titleDoes EBV alter the pathogenesis of malaria
dc.typeJournal Article
dc.source.journaltitleParasite immunology
dc.source.volume37
dc.source.issue9
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/faculty_pubs/1361
dc.identifier.contextkey10382260
html.description.abstract<p>Plasmodium falciparum infections have been implicated in immune deficiencies resulting in ineffective control of Epstein-Barr virus, thereby increasing the risk of endemic Burkitt lymphoma in children. However, the impact of Epstein-Barr virus infections on the development of immunity to P. falciparum has not been studied in depth. In this review, we examine novel findings from animal co-infection models and human immuno-epidemiologic studies to speculate on the impact of acute gammaherpesvirus co-infection on malarial disease severity. Children are often concurrently or sequentially infected with multiple pathogens, and this has implications for understanding the development of protective immunity as well as in the evaluation of vaccine efficacy.</p>
dc.identifier.submissionpathfaculty_pubs/1361
dc.contributor.departmentProgram in Molecular Medicine
dc.source.pages433-45


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