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dc.contributor.authorLe, Xiuning
dc.contributor.authorJain, Preetesh
dc.contributor.authorO'Brien, Susan L.
dc.date2022-08-11T08:08:23.000
dc.date.accessioned2022-08-23T15:53:02Z
dc.date.available2022-08-23T15:53:02Z
dc.date.issued2013-03-01
dc.date.submitted2013-07-08
dc.identifier.citation<p>Am J Hematol. 2013 Mar;88(3):242. doi: 10.1002/ajh.23332. Epub 2012 Oct 13. <a href="http://dx.doi.org/10.1002/ajh.23332">Link to article on publisher's site</a></p>
dc.identifier.issn0361-8609 (Linking)
dc.identifier.doi10.1002/ajh.23332
dc.identifier.pmid23065937
dc.identifier.urihttp://hdl.handle.net/20.500.14038/29270
dc.description.abstractA 35-year-old female received multiagent induction chemotherapy including corticosteroids for acute lymphoblastic leukemia. Around day 20 of her chemotherapy, she developed progressive dry cough, low-grade fever, and hoarseness. It appeared that she has a foreign body in her throat. However, her sputum culture grew Aspergillus terrus. Computed tomographic imaging of her chest revealed circumferential thickening of trachea and left main stem bronchus with endoluminal densities compatible with sloughed-off material (Image 1, arrow). Under bronchoscopic examination, a large white necrotic but firm pseudomembrane was found to obstruct the trachea up to 80% (Image 2) and the pseudomembranous mass was removed. Histopathology of the tissue confirmed extensive deposition of fungal-hyphae.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=23065937&dopt=Abstract">Link to Article in PubMed</a></p>
dc.relation.urlhttp://dx.doi.org/10.1002/ajh.23332
dc.subjectAdult
dc.subjectAspergillosis
dc.subjectFemale
dc.subjectHumans
dc.subjectNecrosis
dc.subjectPrecursor Cell Lymphoblastic
dc.subjectLeukemia-Lymphoma
dc.subjectTracheitis
dc.subjectBacterial Infections and Mycoses
dc.subjectFungi
dc.subjectHematology
dc.subjectHemic and Lymphatic Diseases
dc.subjectRespiratory Tract Diseases
dc.subjectTherapeutics
dc.titleAspergillus pseudomembranous necrotizing tracheitis
dc.typeCase Report
dc.source.volume88
dc.source.issue3
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/faculty_pubs/150
dc.identifier.contextkey4295170
html.description.abstract<p>A 35-year-old female received multiagent induction chemotherapy including corticosteroids for acute lymphoblastic leukemia. Around day 20 of her chemotherapy, she developed progressive dry cough, low-grade fever, and hoarseness. It appeared that she has a foreign body in her throat. However, her sputum culture grew Aspergillus terrus. Computed tomographic imaging of her chest revealed circumferential thickening of trachea and left main stem bronchus with endoluminal densities compatible with sloughed-off material (Image 1, arrow). Under bronchoscopic examination, a large white necrotic but firm pseudomembrane was found to obstruct the trachea up to 80% (Image 2) and the pseudomembranous mass was removed. Histopathology of the tissue confirmed extensive deposition of fungal-hyphae.</p>
dc.identifier.submissionpathfaculty_pubs/150
dc.contributor.departmentInternal Medicine Department
dc.source.pages242


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