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dc.contributor.authorJoormann, Jutta
dc.contributor.authorHaran, John P
dc.date2022-08-11T08:08:26.000
dc.date.accessioned2022-08-23T15:55:20Z
dc.date.available2022-08-23T15:55:20Z
dc.date.issued2020-10-29
dc.date.submitted2021-03-22
dc.identifier.citation<p>Joormann J, McLean SA, Beaudoin FL, An X, Stevens JS, Zeng D, Neylan TC, Clifford G, Linnstaedt SD, Germine LT, Rauch SL, Musey PI, Hendry PL, Sheikh S, Jones CW, Punches BE, Fermann G, Hudak LA, Mohiuddin K, Murty V, McGrath ME, Haran JP, Pascual J, Seamon M, Peak DA, Pearson C, Domeier RM, Sergot P, Merchant R, Sanchez LD, Rathlev NK, Peacock WF, Bruce SE, Barch D, Pizzagalli DA, Luna B, Harte SE, Hwang I, Lee S, Sampson N, Koenen KC, Ressler KJ, Kessler RC. Socio-demographic and trauma-related predictors of depression within eight weeks of motor vehicle collision in the AURORA study. Psychol Med. 2020 Oct 29:1-14. doi: 10.1017/S0033291720003773. Epub ahead of print. PMID: 33118917. <a href="https://doi.org/10.1017/S0033291720003773">Link to article on publisher's site</a></p>
dc.identifier.issn0033-2917 (Linking)
dc.identifier.doi10.1017/S0033291720003773
dc.identifier.pmid33118917
dc.identifier.urihttp://hdl.handle.net/20.500.14038/29730
dc.description.abstractBACKGROUND: This is the first report on the association between trauma exposure and depression from the Advancing Understanding of RecOvery afteR traumA(AURORA) multisite longitudinal study of adverse post-traumatic neuropsychiatric sequelae (APNS) among participants seeking emergency department (ED) treatment in the aftermath of a traumatic life experience. METHODS: We focus on participants presenting at EDs after a motor vehicle collision (MVC), which characterizes most AURORA participants, and examine associations of participant socio-demographics and MVC characteristics with 8-week depression as mediated through peritraumatic symptoms and 2-week depression. RESULTS: Eight-week depression prevalence was relatively high (27.8%) and associated with several MVC characteristics (being passenger v. driver; injuries to other people). Peritraumatic distress was associated with 2-week but not 8-week depression. Most of these associations held when controlling for peritraumatic symptoms and, to a lesser degree, depressive symptoms at 2-weeks post-trauma. CONCLUSIONS: These observations, coupled with substantial variation in the relative strength of the mediating pathways across predictors, raises the possibility of diverse and potentially complex underlying biological and psychological processes that remain to be elucidated in more in-depth analyses of the rich and evolving AURORA database to find new targets for intervention and new tools for risk-based stratification following trauma exposure.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=33118917&dopt=Abstract">Link to Article in PubMed</a></p>
dc.relation.urlhttps://doi.org/10.1017/s0033291720003773
dc.subjectAnxiety
dc.subjectPTSD
dc.subjectdepression
dc.subjecttrauma
dc.subjectEmergency Medicine
dc.subjectMental and Social Health
dc.subjectPsychiatry and Psychology
dc.subjectTrauma
dc.titleSocio-demographic and trauma-related predictors of depression within eight weeks of motor vehicle collision in the AURORA study
dc.typeJournal Article
dc.source.journaltitlePsychological medicine
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/faculty_pubs/1942
dc.identifier.contextkey22133092
html.description.abstract<p>BACKGROUND: This is the first report on the association between trauma exposure and depression from the Advancing Understanding of RecOvery afteR traumA(AURORA) multisite longitudinal study of adverse post-traumatic neuropsychiatric sequelae (APNS) among participants seeking emergency department (ED) treatment in the aftermath of a traumatic life experience.</p> <p>METHODS: We focus on participants presenting at EDs after a motor vehicle collision (MVC), which characterizes most AURORA participants, and examine associations of participant socio-demographics and MVC characteristics with 8-week depression as mediated through peritraumatic symptoms and 2-week depression.</p> <p>RESULTS: Eight-week depression prevalence was relatively high (27.8%) and associated with several MVC characteristics (being passenger v. driver; injuries to other people). Peritraumatic distress was associated with 2-week but not 8-week depression. Most of these associations held when controlling for peritraumatic symptoms and, to a lesser degree, depressive symptoms at 2-weeks post-trauma.</p> <p>CONCLUSIONS: These observations, coupled with substantial variation in the relative strength of the mediating pathways across predictors, raises the possibility of diverse and potentially complex underlying biological and psychological processes that remain to be elucidated in more in-depth analyses of the rich and evolving AURORA database to find new targets for intervention and new tools for risk-based stratification following trauma exposure.</p>
dc.identifier.submissionpathfaculty_pubs/1942
dc.contributor.departmentDepartment of Emergency Medicine
dc.source.pages1-14


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