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    Treating hypertension in patients with left ventricular dysfunction: hitting the fairway and avoiding the rough

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    Authors
    Joffe, Samuel W.
    Phillips, Robert A.
    UMass Chan Affiliations
    Department of Medicine, Division of Cardiovascular Medicine
    Document Type
    Journal Article
    Publication Date
    2013-06-01
    Keywords
    Antihypertensive Agents
    Heart Failure
    Humans
    Hypertension
    Ventricular Dysfunction, Left
    Cardiology
    Cardiovascular Diseases
    
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    Link to Full Text
    http://dx.doi.org/10.1007/s11897-013-0137-9
    Abstract
    Hypertension is a major risk factor in the development of heart failure (HF), yet current guidelines do not specify a target blood pressure (BP) for patients with established systolic or diastolic left ventricular (LV) dysfunction. While no randomized controlled trial (RCT) has been conducted to specify the optimal blood pressure in these patients, numerous trials have demonstrated the benefits of certain classes of medications and treatment strategies in patients with HF. Important factors to consider in treating hypertension in patients with HF include the type of HF (reduced vs. preserved ejection fraction), the etiology (ischemic vs. nonischemic), the severity of symptoms if any, the baseline blood pressure, as well as a wide variety of patient-specific factors. This paper reviews current evidence to address the question, "What should be the blood pressure goal in patients with asymptomatic and symptomatic left ventricular dysfunction?" We suggest a target blood pressure of 120-140/70-90 mm Hg in most cases, with lower pressures generally preferable if tolerated.
    Source
    Joffe SW, Phillips RA. Treating hypertension in patients with left ventricular dysfunction: hitting the fairway and avoiding the rough. Curr Heart Fail Rep. 2013 Jun;10(2):157-64. doi: 10.1007/s11897-013-0137-9. Link to article on publisher's site
    DOI
    10.1007/s11897-013-0137-9
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/30161
    PubMed ID
    23563890
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1007/s11897-013-0137-9
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