Preclinical investigations for thrombectomy devices--does it translate to humans

Authors
Gounis, Matthew J.
Wakhloo, Ajay K.
Chueh, Juyu
UMass Chan Affiliations
Department of Radiology
Document Type
Journal Article
Publication Date
2013-06-05
Keywords
Angiography, Digital Subtraction
Animals
Cerebral Angiography
Cerebrovascular Circulation
Device Approval
Disease Models, Animal
Dogs
Female
Humans
Male

Metadata
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Link to Full Text
http://dx.doi.org/10.1161/STROKEAHA.111.000692
Abstract
Currently, most preclinical models to validate thrombectomy technologies have not directly translated to the clinical arena. Herein, we review our strategy that combines in vitro and in vivo modeling to assess thrombectomy device safety and efficacy quantitatively.
Source
Gounis MJ, Wakhloo AK, Chueh JY. Preclinical investigations for thrombectomy devices--does it translate to humans? Stroke. 2013 Jun;44(6 Suppl 1):S7-S10. doi: 10.1161/STROKEAHA.111.000692. Link to article on publisher's site
DOI
10.1161/STROKEAHA.111.000692
Permanent Link to this Item
http://hdl.handle.net/20.500.14038/30170
PubMed ID
23709736
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