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Preclinical investigations for thrombectomy devices--does it translate to humans

dc.contributor.authorGounis, Matthew J.
dc.contributor.authorWakhloo, Ajay K.
dc.contributor.authorChueh, Juyu
dc.date2022-08-11T08:08:30.000
dc.date.accessioned2022-08-23T15:57:19Z
dc.date.available2022-08-23T15:57:19Z
dc.date.issued2013-06-05
dc.date.submitted2014-05-13
dc.identifier.citationGounis MJ, Wakhloo AK, Chueh JY. Preclinical investigations for thrombectomy devices--does it translate to humans? Stroke. 2013 Jun;44(6 Suppl 1):S7-S10. doi: 10.1161/STROKEAHA.111.000692. <a href="http://dx.doi.org/10.1161/STROKEAHA.111.000692">Link to article on publisher's site</a>
dc.identifier.issn0039-2499 (Linking)
dc.identifier.doi10.1161/STROKEAHA.111.000692
dc.identifier.pmid23709736
dc.identifier.urihttp://hdl.handle.net/20.500.14038/30170
dc.description.abstractCurrently, most preclinical models to validate thrombectomy technologies have not directly translated to the clinical arena. Herein, we review our strategy that combines in vitro and in vivo modeling to assess thrombectomy device safety and efficacy quantitatively.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=23709736&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1161/STROKEAHA.111.000692
dc.subjectAngiography, Digital Subtraction
dc.subjectAnimals
dc.subjectCerebral Angiography
dc.subjectCerebrovascular Circulation
dc.subjectDevice Approval
dc.subjectDisease Models, Animal
dc.subjectDogs
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMicroscopy, Electron, Scanning
dc.subjectModels, Anatomic
dc.subjectSafety
dc.subjectStroke
dc.subjectThrombectomy
dc.subjectUnited States
dc.subjectUnited States Food and Drug Administration
dc.subjectAcute ischemic stroke
dc.subjectclot
dc.subjectembolic shower
dc.subjectpreclinical modeling
dc.subjectrecanalization
dc.subjectthrombectomy
dc.subjectCardiovascular Diseases
dc.subjectNervous System Diseases
dc.subjectNeurology
dc.subjectRadiology
dc.subjectSurgical Procedures, Operative
dc.titlePreclinical investigations for thrombectomy devices--does it translate to humans
dc.typeJournal Article
dc.source.journaltitleStroke; a journal of cerebral circulation
dc.source.volume44
dc.source.issue6 Suppl 1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/faculty_pubs/412
dc.identifier.contextkey5574396
html.description.abstract<p>Currently, most preclinical models to validate thrombectomy technologies have not directly translated to the clinical arena. Herein, we review our strategy that combines in vitro and in vivo modeling to assess thrombectomy device safety and efficacy quantitatively.</p>
dc.identifier.submissionpathfaculty_pubs/412
dc.contributor.departmentDepartment of Radiology
dc.source.pagesS7-S10


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