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    A perspective on recurrent vertigo

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    Authors
    Gacek, Richard R.
    UMass Chan Affiliations
    Department of Otolaryngology
    Document Type
    Journal Article
    Publication Date
    2013-07-01
    Keywords
    Humans
    *Meniere Disease
    Recurrence
    Vertigo
    *Vestibular Neuronitis
    Vertigo
    Viral etiology
    Positional vertigo
    Nervous System Diseases
    Otolaryngology
    Otorhinolaryngologic Diseases
    Pathological Conditions, Signs and Symptoms
    Therapeutics
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    Link to Full Text
    https://doi.org/10.1159/000348710
    Abstract
    The recurrent nature of the 3 most common vestibulopathies suggests a recurrent cause. Histopathology in temporal bones from patients with these syndromes - vestibular neuronitis (VN, n = 7), Meniere's disease (MD, n = 8) and benign paroxysmal positional vertigo (BPPV, n = 5) - shows focal degeneration of vestibular nerve axons and degenerated nearby facial nerve meatal ganglion cells. Transmission electron microscopic confirmation of intracytoplasmic viral particles in surgically excised vestibular nerves from patients with VN and MD support a viral etiology in these vestibulopathies. Antiviral treatment of these syndromes in a series of 211 patients with a 3- to 8-year follow-up resulted in complete control of vertigo in VN (88%), MD (90%) and BPPV (60%).
    Source

    Gacek RR. A perspective on recurrent vertigo. ORL J Otorhinolaryngol Relat Spec. 2013;75(2):91-107. doi: 10.1159/000348710. Link to article on publisher's site

    DOI
    10.1159/000348710
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/30171
    PubMed ID
    23796949
    Related Resources

    Link to Article in PubMed

    ae974a485f413a2113503eed53cd6c53
    10.1159/000348710
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