UMass Chan Affiliations
Department of Medicine, Division of Infectious Diseases and ImmunologyDocument Type
Journal ArticlePublication Date
2013-11-05Keywords
AnimalsBiolistics
Electroporation
Humans
Immunization
Injections
Vaccines, DNA
DNA vaccine
electroporation
gene gun
immunization
Immunoprophylaxis and Therapy
Metadata
Show full item recordAbstract
DNA immunization was discovered in early 1990s, and its use has been expanded from vaccine studies to a broader range of biomedical research areas, such as the generation of high-quality polyclonal and monoclonal antibodies as research reagents. In this unit, three common DNA immunization methods are described: needle injection, electroporation, and gene gun. In addition, several common considerations related to DNA immunization are discussed.Source
Curr Protoc Microbiol. 2013 Nov 5;31:18.3.1-18.3.24. doi:10.1002/9780471729259.mc1803s31. Link to article on publisher's siteDOI
10.1002/9780471729259.mc1803s31Permanent Link to this Item
http://hdl.handle.net/20.500.14038/30513PubMed ID
24510291Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1002/9780471729259.mc1803s31