Clinical epidemiology of heart failure with preserved ejection fraction (HFpEF) in comparatively young hospitalized patients
dc.contributor.author | Zacharias, Michael | |
dc.contributor.author | Joffe, Samuel | |
dc.contributor.author | Konadu, Elizabeth | |
dc.contributor.author | Meyer, Theo E. | |
dc.contributor.author | Kiernan, MIchael S. | |
dc.contributor.author | Lessard, Darleen M. | |
dc.contributor.author | Goldberg, Robert J. | |
dc.date | 2022-08-11T08:08:33.000 | |
dc.date.accessioned | 2022-08-23T15:58:56Z | |
dc.date.available | 2022-08-23T15:58:56Z | |
dc.date.issued | 2016-01-01 | |
dc.date.submitted | 2016-01-07 | |
dc.identifier.citation | <p>Int J Cardiol. 2016 Jan 1;202:918-21. doi: 10.1016/j.ijcard.2015.09.114. Epub 2015 Oct 22. <a href="http://dx.doi.org/10.1016/j.ijcard.2015.09.114">Link to article on publisher's site</a></p> | |
dc.identifier.issn | 0167-5273 (Linking) | |
dc.identifier.doi | 10.1016/j.ijcard.2015.09.114 | |
dc.identifier.pmid | 26479959 | |
dc.identifier.uri | http://hdl.handle.net/20.500.14038/30549 | |
dc.description.abstract | BACKGROUND: While heart failure with preserved ejection fraction (HFpEF) is primarily a disease of old age, risk factors that contribute to HFpEF are not limited to older patients. The objectives of this population-based observational study were to describe the clinical epidemiology of HFpEF in younger ( < 65years) as compared with older ( > /=65years) patients hospitalized with acute decompensated heart failure. METHODS AND RESULTS: We reviewed the medical records of residents of central Massachusetts hospitalized with HFpEF at all 11 greater Worcester (MA) medical centers during the 5 study years of 1995, 2000, 2002, 2004, and 2006. Among the 2398 patients hospitalized with confirmed HFpEF, 357 (14.9%) were < 65years old. Younger patients were more likely to be male, non-Caucasian, obese, and to have a history of diabetes and chronic kidney disease than older patients with HFpEF. Younger patients hospitalized with HFpEF were less likely to have received commonly prescribed cardiac medications, had a longer hospital stay, and experienced significantly lower post-discharge death rates than older hospitalized patients. CONCLUSION: While HFpEF is predominantly a disease of old age, data from longitudinal studies remain needed to identify risk factors in younger individuals that may predispose them to the development of HFpEF. | |
dc.language.iso | en_US | |
dc.relation | <p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=26479959&dopt=Abstract">Link to Article in PubMed</a></p> | |
dc.relation.url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656064/ | |
dc.subject | UMCCTS funding | |
dc.subject | Cardiology | |
dc.subject | Cardiovascular Diseases | |
dc.subject | Clinical Epidemiology | |
dc.title | Clinical epidemiology of heart failure with preserved ejection fraction (HFpEF) in comparatively young hospitalized patients | |
dc.type | Journal Article | |
dc.source.journaltitle | International journal of cardiology | |
dc.source.volume | 202 | |
dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/faculty_pubs/825 | |
dc.identifier.contextkey | 7992964 | |
html.description.abstract | <p>BACKGROUND: While heart failure with preserved ejection fraction (HFpEF) is primarily a disease of old age, risk factors that contribute to HFpEF are not limited to older patients. The objectives of this population-based observational study were to describe the clinical epidemiology of HFpEF in younger ( < 65years) as compared with older ( > /=65years) patients hospitalized with acute decompensated heart failure.</p> <p>METHODS AND RESULTS: We reviewed the medical records of residents of central Massachusetts hospitalized with HFpEF at all 11 greater Worcester (MA) medical centers during the 5 study years of 1995, 2000, 2002, 2004, and 2006. Among the 2398 patients hospitalized with confirmed HFpEF, 357 (14.9%) were < 65years old. Younger patients were more likely to be male, non-Caucasian, obese, and to have a history of diabetes and chronic kidney disease than older patients with HFpEF. Younger patients hospitalized with HFpEF were less likely to have received commonly prescribed cardiac medications, had a longer hospital stay, and experienced significantly lower post-discharge death rates than older hospitalized patients.</p> <p>CONCLUSION: While HFpEF is predominantly a disease of old age, data from longitudinal studies remain needed to identify risk factors in younger individuals that may predispose them to the development of HFpEF.</p> | |
dc.identifier.submissionpath | faculty_pubs/825 | |
dc.contributor.department | Department of Quantitative Health Sciences | |
dc.contributor.department | Department of Medicine, Division of Cardiovascular Medicine | |
dc.source.pages | 918-21 |