Gaps in Knowledge and Research Priorities for Alcoholic Hepatitis
UMass Chan Affiliations
Department of Medicine, Division of GastroenterologyDocument Type
Response or CommentPublication Date
2015-07-01
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Show full item recordAbstract
Alcoholic hepatitis (AH) is a clinical syndrome that was classically characterized by increasing jaundice, hepatomegaly, fever, neutrophilia, and an aspartate aminotransferase (AST):alanine aminotransferase (ALT) ratio of >2. It is a major cause of liver-related hospitalizations in those with a history of heavy alcohol consumption and is also a leading etiology associated with recurrent hospitalizations. Unfortunately, despite its clinical relevance, there are many gaps in knowledge related to this syndrome that represent barriers to the development of effective preventive surveillance, early detection, and therapeutic strategies. This article summarizes the gaps in knowledge and identifies research priorities to fill these gaps.Source
Gastroenterology. 2015 Jul;149(1):4-9. doi: 10.1053/j.gastro.2015.05.015. Epub 2015 May 23. Link to article on publisher's siteDOI
10.1053/j.gastro.2015.05.015Permanent Link to this Item
http://hdl.handle.net/20.500.14038/30687PubMed ID
26008859Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1053/j.gastro.2015.05.015