Neighborhood socioeconomic deprivation and mortality: NIH-AARP diet and health study
AuthorsMajor, Jacqueline M.
Doubeni, Chyke A.
Freedman, Neal D.
Hollenbeck, Albert R.
Graubard, Barry I.
UMass Chan AffiliationsMeyers Primary Care Institute
Department of Family Medicine and Community Health
Document TypeJournal Article
National Institutes of Health (U.S.)
Principal Component Analysis
Proportional Hazards Models
Community Health and Preventive Medicine
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AbstractPURPOSE: Residing in deprived areas may increase risk of mortality beyond that explained by a person's own SES-related factors and lifestyle. The aim of this study was to examine the relation between neighborhood socioeconomic deprivation and all-cause, cancer- and cardiovascular disease (CVD)-specific mortality for men and women after accounting for education and other important person-level risk factors. METHODS: In the longitudinal NIH-AARP Study, we analyzed data from healthy participants, ages 50-71 years at study baseline (1995-1996). Deaths (n = 33831) were identified through December 2005. Information on census tracts was obtained from the 2000 US Census. Cox models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for quintiles of neighborhood deprivation. RESULTS: Participants in the highest quintile of deprivation had elevated risks for overall mortality (HR(men) = 1.17, 95% CI: 1.10, 1.24; HR(women) = 1.13, 95% CI: 1.05, 1.22) and marginally increased risk for cancer deaths (HR(men) = 1.09, 95% CI: 1.00, 1.20; HR(women) = 1.09, 95% CI: 0.99, 1.22). CVD mortality associations appeared stronger in men (HR = 1.33, 95% CI: 1.19, 1.49) than women (HR = 1.18, 95% CI: 1.01, 1.38). There was no evidence of an effect modification by education. CONCLUSION: Higher neighborhood deprivation was associated with modest increases in all-cause, cancer- and CVD-mortality after accounting for many established risk factors.
SourcePLoS One. 2010 Nov 23;5(11):e15538. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/30840
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