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dc.contributor.authorShaw, William S.
dc.contributor.authorMeans-Christensen, Adrienne J.
dc.contributor.authorSlater, Mark A.
dc.contributor.authorWebster, John S.
dc.contributor.authorPatterson, Thomas L.
dc.contributor.authorGrant, Igor
dc.contributor.authorGarfin, Steven R.
dc.contributor.authorWahlgren, Dennis R.
dc.contributor.authorPatel, Shetal
dc.contributor.authorAtkinson, J. Hampton
dc.date2022-08-11T08:08:35.000
dc.date.accessioned2022-08-23T16:00:30Z
dc.date.available2022-08-23T16:00:30Z
dc.date.issued2010-08-23
dc.date.submitted2012-05-21
dc.identifier.citation2010 Aug 23. <a href="http://dx.doi.org/10.1111/j.1526-4637.2010.00934.x">Link to article on publisher's site</a>
dc.identifier.issn1526-2375 (Linking)
dc.identifier.doi10.1111/j.1526-4637.2010.00934.x
dc.identifier.pmid20735749
dc.identifier.urihttp://hdl.handle.net/20.500.14038/30895
dc.description.abstractOBJECTIVE: To assess whether pre-existing psychiatric diagnoses increase the likelihood of transitioning from sub-acute to chronic back pain. DESIGN: Prospective cohort study. METHODS: Men (N = 140) experiencing a first onset of low back pain (LBP) were examined for lifetime psychiatric disorders approximately 8 weeks post pain-onset using the Diagnostic Interview Schedule (DIS-III-R), then re-evaluated at 6 months after pain onset to determine who did or did not progress to pain chronicity. OUTCOME MEASURE: Transition to chronic pain and disability was based on 6-month self-report measures of pain intensity and perceived disability. RESULTS: Men with a pre-pain lifetime diagnosis of major depressive disorder had 5 times greater risk of transitioning to chronic LBP (odds ratio [OR] = 4.99; 95% confidence interval [CI] 1.49-16.76). Increased risk was also associated with a pre-pain lifetime diagnosis of generalized anxiety (OR = 2.45; 95% CI 1.06-5.68), post-traumatic stress (OR = 3.23; 95% CI 1.11-9.44), and with current nicotine dependence (OR = 2.49; 95% CI 1.15-5.40). There were no statistically significant effects for abuse or dependence of alcohol or other psychoactive substances. DISCUSSION: Lifetime history of major depression or a major anxiety disorder may represent potential psychosocial "yellow flags" for the transition to chronicity in men with first-onset LBP. Screening for lifetime depressive or anxiety disorders may identify individuals at higher risk, who may benefit from referral for more intensive rehabilitation.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=20735749&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1111/j.1526-4637.2010.00934.x
dc.subjectAdolescent
dc.subjectAdult
dc.subjectChronic Disease
dc.subjectHumans
dc.subjectLow Back Pain
dc.subjectMale
dc.subjectMental Disorders
dc.subjectMiddle Aged
dc.subjectPain Measurement
dc.subjectPsychiatric Status Rating Scales
dc.subjectRisk Factors
dc.subjectTobacco Use Disorder
dc.subjectYoung Adult
dc.subjectCommunity Health and Preventive Medicine
dc.subjectPreventive Medicine
dc.subjectPrimary Care
dc.titlePsychiatric disorders and risk of transition to chronicity in men with first onset low back pain
dc.typeJournal Article
dc.source.journaltitlePain medicine (Malden, Mass.)
dc.source.volume11
dc.source.issue9
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/fmch_articles/221
dc.identifier.contextkey2879133
html.description.abstract<p>OBJECTIVE: To assess whether pre-existing psychiatric diagnoses increase the likelihood of transitioning from sub-acute to chronic back pain. DESIGN: Prospective cohort study.</p> <p>METHODS: Men (N = 140) experiencing a first onset of low back pain (LBP) were examined for lifetime psychiatric disorders approximately 8 weeks post pain-onset using the Diagnostic Interview Schedule (DIS-III-R), then re-evaluated at 6 months after pain onset to determine who did or did not progress to pain chronicity.</p> <p>OUTCOME MEASURE: Transition to chronic pain and disability was based on 6-month self-report measures of pain intensity and perceived disability.</p> <p>RESULTS: Men with a pre-pain lifetime diagnosis of major depressive disorder had 5 times greater risk of transitioning to chronic LBP (odds ratio [OR] = 4.99; 95% confidence interval [CI] 1.49-16.76). Increased risk was also associated with a pre-pain lifetime diagnosis of generalized anxiety (OR = 2.45; 95% CI 1.06-5.68), post-traumatic stress (OR = 3.23; 95% CI 1.11-9.44), and with current nicotine dependence (OR = 2.49; 95% CI 1.15-5.40). There were no statistically significant effects for abuse or dependence of alcohol or other psychoactive substances.</p> <p>DISCUSSION: Lifetime history of major depression or a major anxiety disorder may represent potential psychosocial "yellow flags" for the transition to chronicity in men with first-onset LBP. Screening for lifetime depressive or anxiety disorders may identify individuals at higher risk, who may benefit from referral for more intensive rehabilitation.</p>
dc.identifier.submissionpathfmch_articles/221
dc.contributor.departmentDepartment of Family Medicine and Community Health
dc.source.pages1391-400


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