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dc.contributor.authorWard, Jeanine
dc.contributor.authorSzabo, Gyongyi
dc.contributor.authorMcManus, David D.
dc.contributor.authorBoyer, Edward W.
dc.date2022-08-11T08:08:36.000
dc.date.accessioned2022-08-23T16:01:11Z
dc.date.available2022-08-23T16:01:11Z
dc.date.issued2011-12-01
dc.date.submitted2012-10-10
dc.identifier.citation<p>J Med Toxicol. 2011 Dec;7(4):288-94. <a href="http://dx.doi.org/10.1007/s13181-011-0189-8" target="_blank">Link to article on publisher's site</a></p>
dc.identifier.issn1556-9039 (Linking)
dc.identifier.doi10.1007/s13181-011-0189-8
dc.identifier.pmid22072091
dc.identifier.urihttp://hdl.handle.net/20.500.14038/31062
dc.description.abstractThe advancement of molecular biologic techniques and their capabilities to answer questions pertaining to mechanisms of pathophysiologic events have greatly expanded over the past few years. In particular, these opportunities have provided researchers and clinicians alike the framework from with which to answer clinical questions not amenable for elucidation using previous, more antiquated methods. Utilizing extremely small molecules, namely microRNA, DNA, protein, and nanoparticles, we discuss the background and utility of these approaches to the progressive, practicing physician. Finally, we consider the application of these tools employed as future bedside point of care tests, aiding in the ultimate goal of unsurpassed patient care.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=22072091&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1007/s13181-011-0189-8
dc.subject*Drug Toxicity
dc.subjectGene Expression Profiling
dc.subjectGenomics
dc.subjectHumans
dc.subjectMetabolomics
dc.subjectMicroRNAs
dc.subjectMolecular Biology
dc.subjectProteomics
dc.subjectSystems Biology
dc.subjectMedical Toxicology
dc.subjectMolecular Biology
dc.subjectToxicology
dc.titleAdvanced molecular biologic techniques in toxicologic disease
dc.typeJournal Article
dc.source.journaltitleJournal of medical toxicology : official journal of the American College of Medical Toxicology
dc.source.volume7
dc.source.issue4
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/gastroenterology_pp/118
dc.identifier.contextkey3383616
html.description.abstract<p>The advancement of molecular biologic techniques and their capabilities to answer questions pertaining to mechanisms of pathophysiologic events have greatly expanded over the past few years. In particular, these opportunities have provided researchers and clinicians alike the framework from with which to answer clinical questions not amenable for elucidation using previous, more antiquated methods. Utilizing extremely small molecules, namely microRNA, DNA, protein, and nanoparticles, we discuss the background and utility of these approaches to the progressive, practicing physician. Finally, we consider the application of these tools employed as future bedside point of care tests, aiding in the ultimate goal of unsurpassed patient care.</p>
dc.identifier.submissionpathgastroenterology_pp/118
dc.contributor.departmentMeyers Primary Care Institute
dc.contributor.departmentDepartment of Medicine, Division of Gastroenterology
dc.contributor.departmentDepartment of Medicine, Division of Cardiovascular Medicine
dc.contributor.departmentDepartment of Emergency Medicine
dc.source.pages288-94


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