HCV immunopathogenesis: virus-induced strategies against host immunity
Name:
Publisher version
View Source
Access full-text PDFOpen Access
View Source
Check access options
Check access options
UMass Chan Affiliations
Department of Medicine, Division of GastroenterologyDocument Type
Journal ArticlePublication Date
2006-12-14Keywords
Antibody FormationHepacivirus
Hepatitis C, Chronic
Humans
Immunity, Innate
Gastroenterology
Hepatology
Metadata
Show full item recordAbstract
Worldwide more than 170 million people are chronically infected with the hepatitis C virus (HCV), which is a frequent cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Unlike infection with other hepatotropic viruses, only a small percentage of acute HCV infections are cleared, and most infected individuals develop lifelong HCV infection in the absence of efficient treatment. It is believed that both viral and host factors contribute to the inability of the host immune system to clear the initial infection and lead to the high propensity of chronic HCV infection.Source
Clin Liver Dis. 2006 Nov;10(4):753-71. Link to article on publisher's siteDOI
10.1016/j.cld.2006.08.028Permanent Link to this Item
http://hdl.handle.net/20.500.14038/31129PubMed ID
17164116Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1016/j.cld.2006.08.028