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UMass Chan Affiliations
Program in Gene Function and ExpressionProgram in Molecular Medicine
Graduate School of Biomedical Sciences
Document Type
Journal ArticlePublication Date
2005-01-12Keywords
Adenosine Triphosphate; Amino Acid Sequence; Animals; Chromatin; DNA-Binding Proteins; *Gene Expression Regulation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosomes; Protein Conformation; Sequence Alignment; Transcription Factors; Transcription, GeneticLife Sciences
Medicine and Health Sciences
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Show full item recordAbstract
The study of chromatin and how this dynamic structure modulates events in the eukaryotic nucleus has become an increasingly important topic in biomedical research. A large number of enzymes have been discovered that are responsible for modifying and altering chromatin structure, either globally or specifically at particular gene promoters or regions of the chromosome. This chapter provides an introduction to the structure of chromatin and then describes how special classes of enzymes modulate chromatin structure to allow access to DNA.Source
Curr Top Dev Biol. 2005;65:115-48. Link to article on publisher's siteDOI
10.1016/S0070-2153(04)65004-6Permanent Link to this Item
http://hdl.handle.net/20.500.14038/32568PubMed ID
15642381Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1016/S0070-2153(04)65004-6