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    Insight into regulatory factor targeting to transcriptionally active subnuclear sites

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    Authors
    Stein, Gary S.
    Van Wijnen, Andre J.
    Stein, Janet L.
    Lian, Jane B.
    Javed, Amjad
    McNeil, Sandra Marie
    Pockwinse, Shirwin M.
    UMass Chan Affiliations
    Department of Cell Biology
    Graduate School of Biomedical Sciences
    Document Type
    Journal Article
    Publication Date
    1999-12-02
    Keywords
    Biological Transport; *Bone Development; Cell Compartmentation; Cell Nucleus; DNA-Binding Proteins; *Hematopoiesis; Transcription Factors
    Life Sciences
    Medicine and Health Sciences
    
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    Link to Full Text
    http://dx.doi.org/10.1006/excr.1999.4680
    Abstract
    Mechanisms that coordinate the spatial organization of genes and regulatory proteins within the three-dimensional context of nuclear architecture contribute to the sorting of regulatory information as well as the assembly and activity of sites within the nucleus that support gene expression. In this article we will present an overview of experimental approaches that provide insight into the trafficking of the hematopoietic and bone-specific AML/CBF family of regulatory factors to transcriptionally active subnuclear sites.
    Source
    Exp Cell Res. 1999 Nov 25;253(1):110-6. Link to article on publisher's site
    DOI
    10.1006/excr.1999.4680
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/32624
    PubMed ID
    10579916
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1006/excr.1999.4680
    Scopus Count
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    Morningside Graduate School of Biomedical Sciences Scholarly Publications

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