Insight into regulatory factor targeting to transcriptionally active subnuclear sites
Authors
Stein, Gary S.Van Wijnen, Andre J.
Stein, Janet L.
Lian, Jane B.
Javed, Amjad
McNeil, Sandra Marie
Pockwinse, Shirwin M.
Document Type
Journal ArticlePublication Date
1999-12-02Keywords
Biological Transport; *Bone Development; Cell Compartmentation; Cell Nucleus; DNA-Binding Proteins; *Hematopoiesis; Transcription FactorsLife Sciences
Medicine and Health Sciences
Metadata
Show full item recordAbstract
Mechanisms that coordinate the spatial organization of genes and regulatory proteins within the three-dimensional context of nuclear architecture contribute to the sorting of regulatory information as well as the assembly and activity of sites within the nucleus that support gene expression. In this article we will present an overview of experimental approaches that provide insight into the trafficking of the hematopoietic and bone-specific AML/CBF family of regulatory factors to transcriptionally active subnuclear sites.Source
Exp Cell Res. 1999 Nov 25;253(1):110-6. Link to article on publisher's siteDOI
10.1006/excr.1999.4680Permanent Link to this Item
http://hdl.handle.net/20.500.14038/32624PubMed ID
10579916Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1006/excr.1999.4680