Induction of angiosarcoma by a c-erbB transducing virus
| dc.contributor.author | Tracy, Sharon Elizabeth | |
| dc.contributor.author | Woda, Bruce A. | |
| dc.contributor.author | Robinson, Harriet L. | |
| dc.date | 2022-08-11T08:08:49.000 | |
| dc.date.accessioned | 2022-08-23T16:09:29Z | |
| dc.date.available | 2022-08-23T16:09:29Z | |
| dc.date.issued | 1985-05-01 | |
| dc.date.submitted | 2009-01-13 | |
| dc.identifier.citation | <p>J Virol. 1985 May;54(2):304-10.</p> | |
| dc.identifier.issn | 0022-538X (Print) | |
| dc.identifier.pmid | 2985799 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14038/32706 | |
| dc.description.abstract | Recently, 12 new transductions of c-erbB have been identified in a series of Rous-associated virus type 1-induced erythroleukemias. During the passage of these new transducing viruses it has become apparent that the erythroleukemia in chicken 5005 contained two different c-erbB transducing viruses. One induces erythroblastosis, whereas the second induces angiosarcoma. The angiosarcoma- and erythroblastosis-inducing viruses appear to have had a common ancestor, since tumors induced by each contain a novel, 4.3-kilobase c-erbB-related EcoRI fragment. The angiosarcoma-inducing virus has been named avian angiosarcoma virus and is designated for the chicken in which it originated. | |
| dc.language.iso | en_US | |
| dc.relation | <p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=2985799&dopt=Abstract">Link to Article in PubMed</a></p> | |
| dc.relation.url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC254798/ | |
| dc.subject | Animals; Avian Leukosis; Avian leukosis virus; Base Sequence; Chickens; Hemangiosarcoma; *Transduction, Genetic | |
| dc.subject | Life Sciences | |
| dc.subject | Medicine and Health Sciences | |
| dc.title | Induction of angiosarcoma by a c-erbB transducing virus | |
| dc.type | Journal Article | |
| dc.source.journaltitle | Journal of virology | |
| dc.source.volume | 54 | |
| dc.source.issue | 2 | |
| dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/gsbs_sp/1262 | |
| dc.identifier.contextkey | 693174 | |
| html.description.abstract | <p>Recently, 12 new transductions of c-erbB have been identified in a series of Rous-associated virus type 1-induced erythroleukemias. During the passage of these new transducing viruses it has become apparent that the erythroleukemia in chicken 5005 contained two different c-erbB transducing viruses. One induces erythroblastosis, whereas the second induces angiosarcoma. The angiosarcoma- and erythroblastosis-inducing viruses appear to have had a common ancestor, since tumors induced by each contain a novel, 4.3-kilobase c-erbB-related EcoRI fragment. The angiosarcoma-inducing virus has been named avian angiosarcoma virus and is designated for the chicken in which it originated.</p> | |
| dc.identifier.submissionpath | gsbs_sp/1262 | |
| dc.contributor.department | Department of Pathology | |
| dc.contributor.department | Graduate School of Biomedical Sciences | |
| dc.source.pages | 304-10 |