The use of immunization registry-based data in vaccine effectiveness studies
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Student Authors
Hilary PlaczekUMass Chan Affiliations
Department of Medicine, Division of Infectious Diseases and ImmunologyDocument Type
Accepted ManuscriptPublication Date
2010-11-16Keywords
Vaccines; Immunization Programs; Registries; Evaluation Studies as TopicImmunology and Infectious Disease
Life Sciences
Medicine and Health Sciences
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Vaccine effectiveness (VE) studies provide a measure of population-based vaccine performance by combining immunization history data with rates of disease incidence. This review assessed the feasibility of using electronic immunization registry data sources in VE studies. Electronic databases were searched through January 31, 2010. Out of 17 studies, only one paper assessed data accuracy (71%), and three papers assessed population coverage of the registry (estimates ranged from 25% to 90%). This review shows that registry-based data sources can be used to conduct VE studies in a variety of settings and populations. However, we found little information regarding the quality of this data source in VE studies and future evaluations should investigate their reliability, accuracy, and potential bias. Copyright © 2010 Elsevier Ltd. All rights reserved.Source
Vaccine, Volume 29, Issue 3, 10 January 2011, Pages 399-411. doi: 10.1016/j.vaccine.2010.11.007. View the publisher’s formatted versionDOI
10.1016/j.vaccine.2010.11.007Permanent Link to this Item
http://hdl.handle.net/20.500.14038/33123PubMed ID
21087687Related Resources
Link to article in PubMedRights
This is the authors' final, peer-reviewed version of the article as prepared for publication in Vaccine, Volume 29, Issue 3, 10 January 2011, Pages 399-411. doi:10.1016/j.vaccine.2010.11.007. View the publisher’s formatted versionae974a485f413a2113503eed53cd6c53
10.1016/j.vaccine.2010.11.007