The MutS C terminus is essential for mismatch repair activity in vivo
| dc.contributor.author | Calmann, Melissa A. | |
| dc.contributor.author | Nowosielska, Anetta | |
| dc.contributor.author | Marinus, Martin G. | |
| dc.date | 2022-08-11T08:08:54.000 | |
| dc.date.accessioned | 2022-08-23T16:11:27Z | |
| dc.date.available | 2022-08-23T16:11:27Z | |
| dc.date.issued | 2005-09-15 | |
| dc.date.submitted | 2008-08-15 | |
| dc.identifier.citation | J Bacteriol. 2005 Sep;187(18):6577-9. <a href="http://dx.doi.org/10.1128/JB.187.18.6577-6579.2005">Link to article on publisher's site</a> | |
| dc.identifier.issn | 0021-9193 (Print) | |
| dc.identifier.doi | 10.1128/JB.187.18.6577-6579.2005 | |
| dc.identifier.pmid | 16159793 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14038/33170 | |
| dc.description.abstract | An Escherichia coli K-12 strain was constructed with a chromosomal deletion (mutSdelta800) in the mutS gene that produced the removal of the C-terminal 53 amino acids which are not present in the MutS crystal structure. This strain has a MutS null phenotype for mutation avoidance, anti-recombination, and sensitivity to cytotoxic agents in a dam mutant background. | |
| dc.language.iso | en_US | |
| dc.relation | <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16159793&dopt=Abstract ">Link to article in PubMed</a> | |
| dc.relation.url | http://dx.doi.org/10.1128/JB.187.18.6577-6579.2005 | |
| dc.subject | Adenosine Triphosphatases; Bacterial Proteins; Base Pair Mismatch; DNA Repair; DNA-Binding Proteins; Escherichia coli; *Escherichia coli Proteins; MutS DNA Mismatch-Binding Protein; *Mutation | |
| dc.subject | Life Sciences | |
| dc.subject | Medicine and Health Sciences | |
| dc.title | The MutS C terminus is essential for mismatch repair activity in vivo | |
| dc.type | Journal Article | |
| dc.source.journaltitle | Journal of bacteriology | |
| dc.source.volume | 187 | |
| dc.source.issue | 18 | |
| dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/gsbs_sp/171 | |
| dc.identifier.contextkey | 580023 | |
| html.description.abstract | <p>An Escherichia coli K-12 strain was constructed with a chromosomal deletion (mutSdelta800) in the mutS gene that produced the removal of the C-terminal 53 amino acids which are not present in the MutS crystal structure. This strain has a MutS null phenotype for mutation avoidance, anti-recombination, and sensitivity to cytotoxic agents in a dam mutant background.</p> | |
| dc.identifier.submissionpath | gsbs_sp/171 | |
| dc.contributor.department | Program in Molecular Medicine | |
| dc.contributor.department | Department of Biochemistry and Molecular Pharmacology | |
| dc.contributor.department | Graduate School of Biomedical Sciences | |
| dc.source.pages | 6577-9 |