Neuronal death or dismemberment mediated by Sox14
| dc.contributor.author | Osterloh, Jeannette M. | |
| dc.contributor.author | Freeman, Marc R. | |
| dc.date | 2022-08-11T08:08:54.000 | |
| dc.date.accessioned | 2022-08-23T16:11:28Z | |
| dc.date.available | 2022-08-23T16:11:28Z | |
| dc.date.issued | 2009-11-26 | |
| dc.date.submitted | 2011-05-20 | |
| dc.identifier.citation | Nat Neurosci. 2009 Dec;12(12):1479-80. <a href="http://dx.doi.org/10.1038/nn1209-1479">Link to article on publisher's site</a> | |
| dc.identifier.issn | 1097-6256 (Linking) | |
| dc.identifier.doi | 10.1038/nn1209-1479 | |
| dc.identifier.pmid | 19935724 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14038/33176 | |
| dc.description.abstract | The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis, the transcription factor Sox14 acts as a context-dependent mediator of death, axonal or dendritic pruning. Its transcriptional target Mical acts specifically in dendrite pruning. | |
| dc.language.iso | en_US | |
| dc.relation | <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=19935724&dopt=Abstract">Link to Article in PubMed</a> | |
| dc.relation.url | http://dx.doi.org/10.1038/nn1209-1479 | |
| dc.subject | Animals; Axons; Cell Differentiation; Dendrites; Drosophila; Drosophila Proteins; Metamorphosis, Biological; Neurons; SOXB2 Transcription Factors | |
| dc.subject | Neuroscience and Neurobiology | |
| dc.title | Neuronal death or dismemberment mediated by Sox14 | |
| dc.type | Journal Article | |
| dc.source.journaltitle | Nature neuroscience | |
| dc.source.volume | 12 | |
| dc.source.issue | 12 | |
| dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/gsbs_sp/1715 | |
| dc.identifier.contextkey | 2022726 | |
| html.description.abstract | <p>The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During <em>Drosophila</em> metamorphosis, the transcription factor Sox14 acts as a context-dependent mediator of death, axonal or dendritic pruning. Its transcriptional target Mical acts specifically in dendrite pruning.</p> | |
| dc.identifier.submissionpath | gsbs_sp/1715 | |
| dc.contributor.department | Graduate School of Biomedical Sciences, Neuroscience Program | |
| dc.contributor.department | Freeman Lab | |
| dc.contributor.department | Neurobiology | |
| dc.source.pages | 1479-80 | |
| dc.contributor.student | Jeannette Osterloh | |
| dc.description.thesisprogram | Neuroscience |