The two CRYs of the butterfly
| dc.contributor.author | Zhu, Haisun | |
| dc.contributor.author | Yuan, Quan | |
| dc.contributor.author | Briscoe, Adriana D. | |
| dc.contributor.author | Froy, Oren | |
| dc.contributor.author | Casselman, Amy L. | |
| dc.contributor.author | Reppert, Steven M. | |
| dc.date | 2022-08-11T08:08:54.000 | |
| dc.date.accessioned | 2022-08-23T16:11:33Z | |
| dc.date.available | 2022-08-23T16:11:33Z | |
| dc.date.issued | 2005-12-08 | |
| dc.date.submitted | 2011-05-20 | |
| dc.identifier.citation | Curr Biol. 2005 Dec 6;15(23):R953-4. <a href="http://dx.doi.org/10.1016/j.cub.2005.11.030">Link to article on publisher's site</a> | |
| dc.identifier.issn | 0960-9822 (Linking) | |
| dc.identifier.doi | 10.1016/j.cub.2005.11.030 | |
| dc.identifier.pmid | 16332522 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14038/33195 | |
| dc.description.abstract | Animal flavoproteins called cryptochromes (CRYs) are generally believed to have distinct circadian clock functions in insects and mammals. We have discovered that the monarch butterfly, Danaus plexippus, has two cry genes: one encodes a fly-like protein with photosensitive properties, while the other encodes a mouse-like protein with potent transcriptional repressive activity. Database searches show that other non-drosophilid insects also have two cry genes. These findings change our view of how some insect clocks may work and redefine the evolution of animal CRYs. | |
| dc.language.iso | en_US | |
| dc.relation | <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=16332522&dopt=Abstract">Link to Article in PubMed</a> | |
| dc.relation.url | http://dx.doi.org/10.1016/j.cub.2005.11.030 | |
| dc.subject | Animals; Biological Clocks; Butterflies; Cell Line; Cryptochromes; DNA, Complementary; Drosophila; Expressed Sequence Tags; Flavoproteins; Gene Expression Regulation; *Light; Luciferases; *Phylogeny | |
| dc.subject | Neuroscience and Neurobiology | |
| dc.title | The two CRYs of the butterfly | |
| dc.type | Journal Article | |
| dc.source.journaltitle | Current biology : CB | |
| dc.source.volume | 15 | |
| dc.source.issue | 23 | |
| dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/gsbs_sp/1733 | |
| dc.identifier.contextkey | 2022744 | |
| html.description.abstract | <p>Animal flavoproteins called cryptochromes (CRYs) are generally believed to have distinct circadian clock functions in insects and mammals. We have discovered that the monarch butterfly, <em>Danaus plexippus</em>, has two <em>cry</em> genes: one encodes a fly-like protein with photosensitive properties, while the other encodes a mouse-like protein with potent transcriptional repressive activity. Database searches show that other non-drosophilid insects also have two <em>cry</em> genes. These findings change our view of how some insect clocks may work and redefine the evolution of animal CRYs.</p> | |
| dc.identifier.submissionpath | gsbs_sp/1733 | |
| dc.contributor.department | Morningside Graduate School of Biomedical Sciences | |
| dc.contributor.department | Reppert Lab | |
| dc.contributor.department | Neurobiology | |
| dc.source.pages | R953-4 | |
| dc.contributor.student | Quan Yuan | |
| dc.description.thesisprogram | Neuroscience |
Files in this item
Name:
Publisher version