Drosophila olfactory memory: single genes to complex neural circuits
Student Authors
Alex KeeneUMass Chan Affiliations
Graduate School of Biomedical Sciences, Neuroscience ProgramWaddell Lab
Neurobiology
Document Type
Journal ArticlePublication Date
2007-05-01Keywords
Animals; Drosophila; Genes, Insect; Memory; Nerve Net; Olfactory PathwaysNeuroscience and Neurobiology
Metadata
Show full item recordAbstract
A central goal of neuroscience is to understand how neural circuits encode memory and guide behaviour. Studying simple, genetically tractable organisms, such as Drosophila melanogaster, can illuminate principles of neural circuit organization and function. Early genetic dissection of D. melanogaster olfactory memory focused on individual genes and molecules. These molecular tags subsequently revealed key neural circuits for memory. Recent advances in genetic technology have allowed us to manipulate and observe activity in these circuits, and even individual neurons, in live animals. The studies have transformed D. melanogaster from a useful organism for gene discovery to an ideal model to understand neural circuit function in memory.Source
Nat Rev Neurosci. 2007 May;8(5):341-54. Link to article on publisher's siteDOI
10.1038/nrn2098Permanent Link to this Item
http://hdl.handle.net/20.500.14038/33944PubMed ID
17453015Related Resources
Link to article in PubMedae974a485f413a2113503eed53cd6c53
10.1038/nrn2098