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    Drosophila olfactory memory: single genes to complex neural circuits

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    Authors
    Keene, Alex Carl
    Waddell, Scott
    Student Authors
    Alex Keene
    Academic Program
    Neuroscience
    UMass Chan Affiliations
    Graduate School of Biomedical Sciences, Neuroscience Program
    Waddell Lab
    Neurobiology
    Document Type
    Journal Article
    Publication Date
    2007-05-01
    Keywords
    Animals; Drosophila; Genes, Insect; Memory; Nerve Net; Olfactory Pathways
    Neuroscience and Neurobiology
    
    Metadata
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    Link to Full Text
    http://dx.doi.org/10.1038/nrn2098
    Abstract
    A central goal of neuroscience is to understand how neural circuits encode memory and guide behaviour. Studying simple, genetically tractable organisms, such as Drosophila melanogaster, can illuminate principles of neural circuit organization and function. Early genetic dissection of D. melanogaster olfactory memory focused on individual genes and molecules. These molecular tags subsequently revealed key neural circuits for memory. Recent advances in genetic technology have allowed us to manipulate and observe activity in these circuits, and even individual neurons, in live animals. The studies have transformed D. melanogaster from a useful organism for gene discovery to an ideal model to understand neural circuit function in memory.
    Source
    Nat Rev Neurosci. 2007 May;8(5):341-54. Link to article on publisher's site
    DOI
    10.1038/nrn2098
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/33944
    PubMed ID
    17453015
    Related Resources
    Link to article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1038/nrn2098
    Scopus Count
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    Morningside GSBS Scholarly Publications
    Neurobiology Student Publications
    Neurobiology Faculty Publications

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