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dc.contributor.authorWebb, Sarah Jane
dc.contributor.authorShell, Alison R.
dc.contributor.authorCuomo, Jason
dc.contributor.authorJensen, Guy
dc.contributor.authorDeutsch, Curtis K.
dc.date2022-08-11T08:09:07.000
dc.date.accessioned2022-08-23T16:18:27Z
dc.date.available2022-08-23T16:18:27Z
dc.date.issued2012-01-01
dc.date.submitted2015-04-12
dc.identifier.citation<p>Webb, S. J., Shell, A. R., Cuomo, J. R., Jensen, G., & Deutsch, C. K. (2012). Head circumference measurement and growth: application to neurodevelopment. In V. R. Preedy (Ed.),<em>Handbook of Growth and Growth Monitoring in Health and Disease</em> (p. 2981-2997)<em>.</em> New York: Springer.</p> <p>DOI: 10.1007/978-1-4419-1795-9_179</p> <p>Link to chapter information on <a href="http://link.springer.com/chapter/10.1007/978-1-4419-1795-9_179#">publisher's site</a>.</p>
dc.identifier.doi10.1007/978-1-4419-1795-9_179
dc.identifier.urihttp://hdl.handle.net/20.500.14038/34817
dc.description.abstractWhole brain volume and head size, estimated by the measurement of occipito-frontal circumference (OFC), have been implicated in a variety of developmental disorders. The goals of this chapter are to review the (a) relation of head growth to general neurodevelopment, (b) growth patterns in premature infants and relation to outcome, (c) overgrowth and its relation to neurodevelopmental disorders, and (d) relation between psychological syndromes and growth patterns. Additionally, this chapter (e) discusses head circumference size and growth in pathologic conditions, focusing on atypical development in overgrowth syndromes and pervasive developmental disorders such as autism. Last, this chapter (f) reviews some practical and technical issues involved in the use of head circumference data for clinical documentation and for research. In summary, increased HC and growth have been found to be associated with higher IQ in neurotypical populations. However, this relationship may more accurately be represented by a U-shaped function, with developmental disorders associated with high and low extremes. In addition, a number of genes have been found to be associated with macrocephaly, which may also contribute to developmental disabilities, including autism. Thus, head circumference may be a useful biological marker for assessing developmental risk and for stratification in genetic analysis.
dc.language.isoen_US
dc.relation.urlhttp://dx.doi.org/10.1007/978-1-4419-1795-9_179
dc.subjectMaternal and Child Health
dc.subjectMedical Anatomy
dc.subjectMental Disorders
dc.subjectMusculoskeletal, Neural, and Ocular Physiology
dc.subjectNervous System
dc.titleHead Circumference Measurement and Growth: Application to Neurodevelopment
dc.typeBook Chapter
dc.source.booktitleHandbook of Growth and Growth Monitoring in Health and Disease
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/iddrc_pubs/39
dc.identifier.contextkey6974009
html.description.abstract<p>Whole brain volume and head size, estimated by the measurement of occipito-frontal circumference (OFC), have been implicated in a variety of developmental disorders. The goals of this chapter are to review the (a) relation of head growth to general neurodevelopment, (b) growth patterns in premature infants and relation to outcome, (c) overgrowth and its relation to neurodevelopmental disorders, and (d) relation between psychological syndromes and growth patterns. Additionally, this chapter (e) discusses head circumference size and growth in pathologic conditions, focusing on atypical development in overgrowth syndromes and pervasive developmental disorders such as autism. Last, this chapter (f) reviews some practical and technical issues involved in the use of head circumference data for clinical documentation and for research. In summary, increased HC and growth have been found to be associated with higher IQ in neurotypical populations. However, this relationship may more accurately be represented by a U-shaped function, with developmental disorders associated with high and low extremes. In addition, a number of genes have been found to be associated with macrocephaly, which may also contribute to developmental disabilities, including autism. Thus, head circumference may be a useful biological marker for assessing developmental risk and for stratification in genetic analysis.</p>
dc.identifier.submissionpathiddrc_pubs/39
dc.contributor.departmentIntellectual and Developmental Disabilities Research Center
dc.contributor.departmentShriver Center


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