The Significance of Isolated Antibody to Hepatitis B Core Antigen Seropositivity in Patients Infected with Human Immunodeficiency Virus
| dc.contributor.author | Davaro, Raul E. | |
| dc.contributor.author | Cheeseman, Sarah H. | |
| dc.contributor.author | Keroack, Mark A. | |
| dc.contributor.author | Ellison, Richard T. III | |
| dc.date | 2022-08-11T08:09:09.000 | |
| dc.date.accessioned | 2022-08-23T16:19:16Z | |
| dc.date.available | 2022-08-23T16:19:16Z | |
| dc.date.issued | 1996-07-01 | |
| dc.date.submitted | 2015-12-23 | |
| dc.identifier.citation | Davaro RE, Cheeseman SH, Keroack MA, Ellison RT III. The significance of isolated anti-HBc seropositivity in patients infected with HIV. Clin Infect Dis 1996;23:189-190. doi: 10.1093/clinids/23.1.189. <a href="http://dx.doi.org/10.1093/clinids/23.1.189">Link to article on publisher's site</a> | |
| dc.identifier.doi | 10.1093/clinids/23.1.189 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14038/35007 | |
| dc.description.abstract | To decrease transmission of hepatitis B virus (HBV), immunization with the HBV vaccine has been recommended for individuals in high-risk populations who are seronegative for antibodies to hepatitis B [1]. Isolated antibody to hepatitis B core antigen (antiHBc) seropositivity is found in about 2.5% of volunteer blood donors in the United States and is often considered a false-positive serological response [2]. However, in a retrospective review of HIV-infected patients in Worcester, Massachusetts, we unexpectedly noted isolated anti-HBc seropositivity in > 30% of our population. To gain insight into the meaning of the isolated anti-HBc seropositivity, we further analyzed this patient population. | |
| dc.language.iso | en_US | |
| dc.relation.url | http://dx.doi.org/10.1093/clinids/23.1.189 | |
| dc.subject | Immunity | |
| dc.subject | Immunology of Infectious Disease | |
| dc.subject | Infectious Disease | |
| dc.title | The Significance of Isolated Antibody to Hepatitis B Core Antigen Seropositivity in Patients Infected with Human Immunodeficiency Virus | |
| dc.type | Journal Article | |
| dc.source.journaltitle | Clinical Infectious Diseases | |
| dc.source.volume | 23 | |
| dc.source.issue | 1 | |
| dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/infdis_pp/225 | |
| dc.identifier.contextkey | 7972081 | |
| html.description.abstract | <p>To decrease transmission of hepatitis B virus (HBV), immunization with the HBV vaccine has been recommended for individuals in high-risk populations who are seronegative for antibodies to hepatitis B [1]. Isolated antibody to hepatitis B core antigen (antiHBc) seropositivity is found in about 2.5% of volunteer blood donors in the United States and is often considered a false-positive serological response [2]. However, in a retrospective review of HIV-infected patients in Worcester, Massachusetts, we unexpectedly noted isolated anti-HBc seropositivity in > 30% of our population. To gain insight into the meaning of the isolated anti-HBc seropositivity, we further analyzed this patient population.</p> | |
| dc.identifier.submissionpath | infdis_pp/225 | |
| dc.contributor.department | Department of Medicine, Division of Infectious Diseases and Immunology | |
| dc.source.pages | 189-190 |