The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus
UMass Chan Affiliations
Department of Medicine, Division of Infectious Diseases and ImmunologyDocument Type
Journal ArticlePublication Date
1996-07-01
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To decrease transmission of hepatitis B virus (HBV), immunization with the HBV vaccine has been recommended for individuals in high-risk populations who are seronegative for antibodies to hepatitis B [1]. Isolated antibody to hepatitis B core antigen (antiHBc) seropositivity is found in about 2.5% of volunteer blood donors in the United States and is often considered a false-positive serological response [2]. However, in a retrospective review of HIV-infected patients in Worcester, Massachusetts, we unexpectedly noted isolated anti-HBc seropositivity in > 30% of our population. To gain insight into the meaning of the isolated anti-HBc seropositivity, we further analyzed this patient population.Source
Davaro RE, Cheeseman SH, Keroack MA, Ellison RT 3rd. The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus. Clin Infect Dis. 1996 Jul;23(1):189-90. doi: 10.1093/clinids/23.1.189. PMID: 8816158. Link to article on publisher's site
DOI
10.1093/clinids/23.1.189Permanent Link to this Item
http://hdl.handle.net/20.500.14038/35184PubMed ID
8816158Related Resources
ae974a485f413a2113503eed53cd6c53
10.1093/clinids/23.1.189