The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus
UMass Chan AffiliationsDepartment of Medicine, Division of Infectious Diseases and Immunology
Document TypeJournal Article
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AbstractTo decrease transmission of hepatitis B virus (HBV), immunization with the HBV vaccine has been recommended for individuals in high-risk populations who are seronegative for antibodies to hepatitis B . Isolated antibody to hepatitis B core antigen (antiHBc) seropositivity is found in about 2.5% of volunteer blood donors in the United States and is often considered a false-positive serological response . However, in a retrospective review of HIV-infected patients in Worcester, Massachusetts, we unexpectedly noted isolated anti-HBc seropositivity in > 30% of our population. To gain insight into the meaning of the isolated anti-HBc seropositivity, we further analyzed this patient population.
Davaro RE, Cheeseman SH, Keroack MA, Ellison RT 3rd. The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus. Clin Infect Dis. 1996 Jul;23(1):189-90. doi: 10.1093/clinids/23.1.189. PMID: 8816158. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/35184