The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus
| dc.contributor.author | Davaro, Raul E. | |
| dc.contributor.author | Cheeseman, Sarah H. | |
| dc.contributor.author | Keroack, Mark A. | |
| dc.contributor.author | Ellison, Richard T. III | |
| dc.date | 2022-08-11T08:09:10.000 | |
| dc.date.accessioned | 2022-08-23T16:20:00Z | |
| dc.date.available | 2022-08-23T16:20:00Z | |
| dc.date.issued | 1996-07-01 | |
| dc.date.submitted | 2020-03-25 | |
| dc.identifier.citation | <p>Davaro RE, Cheeseman SH, Keroack MA, Ellison RT 3rd. The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus. Clin Infect Dis. 1996 Jul;23(1):189-90. doi: 10.1093/clinids/23.1.189. PMID: 8816158. <a href="https://doi.org/10.1093/clinids/23.1.189">Link to article on publisher's site</a></p> | |
| dc.identifier.issn | 1058-4838 (Linking) | |
| dc.identifier.doi | 10.1093/clinids/23.1.189 | |
| dc.identifier.pmid | 8816158 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14038/35184 | |
| dc.description.abstract | To decrease transmission of hepatitis B virus (HBV), immunization with the HBV vaccine has been recommended for individuals in high-risk populations who are seronegative for antibodies to hepatitis B [1]. Isolated antibody to hepatitis B core antigen (antiHBc) seropositivity is found in about 2.5% of volunteer blood donors in the United States and is often considered a false-positive serological response [2]. However, in a retrospective review of HIV-infected patients in Worcester, Massachusetts, we unexpectedly noted isolated anti-HBc seropositivity in > 30% of our population. To gain insight into the meaning of the isolated anti-HBc seropositivity, we further analyzed this patient population. | |
| dc.language.iso | en_US | |
| dc.relation | <p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=8816158&dopt=Abstract">Link to Article in PubMed</a></p> | |
| dc.relation.url | https://doi.org/10.1093/clinids/23.1.189 | |
| dc.subject | Immunology and Infectious Disease | |
| dc.subject | Infectious Disease | |
| dc.subject | Virus Diseases | |
| dc.title | The significance of isolated antibody to hepatitis B core antigen seropositivity in patients infected with human immunodeficiency virus | |
| dc.type | Journal Article | |
| dc.source.journaltitle | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | |
| dc.source.volume | 23 | |
| dc.source.issue | 1 | |
| dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/infdis_pp/409 | |
| dc.identifier.contextkey | 17052206 | |
| html.description.abstract | <p>To decrease transmission of hepatitis B virus (HBV), immunization with the HBV vaccine has been recommended for individuals in high-risk populations who are seronegative for antibodies to hepatitis B [1]. Isolated antibody to hepatitis B core antigen (antiHBc) seropositivity is found in about 2.5% of volunteer blood donors in the United States and is often considered a false-positive serological response [2]. However, in a retrospective review of HIV-infected patients in Worcester, Massachusetts, we unexpectedly noted isolated anti-HBc seropositivity in > 30% of our population. To gain insight into the meaning of the isolated anti-HBc seropositivity, we further analyzed this patient population.</p> | |
| dc.identifier.submissionpath | infdis_pp/409 | |
| dc.contributor.department | Department of Medicine, Division of Infectious Diseases and Immunology | |
| dc.source.pages | 189-90 |