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UMass Chan Affiliations
Department of Medicine, Division of Infectious Diseases and ImmunologyDocument Type
Journal ArticlePublication Date
2018-10-10
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Show full item recordAbstract
Early detection of microbial patterns is a hallmark of innate immunity and essential for clearance of invading pathogens. A recent Nature publication by Zhou et al. (2018) has uncovered ALPK1 as a pattern recognition receptor for Gram-negative bacteria triggering NF-kappaB activation and identified the bacterial sugar ADP-Hep as its ligand.Source
Orning P, Flo TH, Lien E. A Sugar Rush for Innate Immunity. Cell Host Microbe. 2018 Oct 10;24(4):461-463. doi: 10.1016/j.chom.2018.09.017. PMID: 30308148; PMCID: PMC6510543. Link to article on publisher's site
DOI
10.1016/j.chom.2018.09.017Permanent Link to this Item
http://hdl.handle.net/20.500.14038/35196PubMed ID
30308148Related Resources
ae974a485f413a2113503eed53cd6c53
10.1016/j.chom.2018.09.017