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UMass Chan Affiliations
Department of Medicine, Division of Infectious Diseases and ImmunologyDocument Type
Journal ArticlePublication Date
2010-05-19
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Show full item recordAbstract
To defend cells against viruses, the MAVS (mitochondrial antiviral signaling) adaptor protein initiates an antiviral signaling cascade from mitochondrial membranes. In this issue, Dixit et al. (2010) show that MAVS also localizes to the membranes of peroxisomes, where it rapidly induces expression of a subset of antiviral genes that curb viral replication until mitochondrial MAVS can induce a sustained antiviral response.Source
Cell. 2010 May 14;141(4):570-2. Link to article on publisher's siteDOI
10.1016/j.cell.2010.04.043Permanent Link to this Item
http://hdl.handle.net/20.500.14038/35212PubMed ID
20478250Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1016/j.cell.2010.04.043