Catenin' on to nucleic acid sensing
| dc.contributor.author | Rathinam, Vijay A.K. | |
| dc.contributor.author | Sharma, Shrutie | |
| dc.contributor.author | Fitzgerald, Katherine A. | |
| dc.date | 2022-08-11T08:09:10.000 | |
| dc.date.accessioned | 2022-08-23T16:20:08Z | |
| dc.date.available | 2022-08-23T16:20:08Z | |
| dc.date.issued | 2010-05-21 | |
| dc.date.submitted | 2011-03-25 | |
| dc.identifier.citation | Nat Immunol. 2010 Jun;11(6):466-8. <a href="http://dx.doi.org/10.1038/ni0610-466">Link to article on publisher's site</a> | |
| dc.identifier.issn | 1529-2908 (Linking) | |
| dc.identifier.doi | 10.1038/ni0610-466 | |
| dc.identifier.pmid | 20485273 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14038/35214 | |
| dc.description.abstract | Many pathogens induce a type I interferon response via a pathway dependent on the kinase TBK1 and transcription factor IRF3. However, LRRFIP1, a cytosolic sensor of DNA and RNA, triggers interferon production by a β-catenin-dependent signal. | |
| dc.language.iso | en_US | |
| dc.relation | <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=20485273&dopt=Abstract">Link to Article in PubMed</a> | |
| dc.relation.url | http://dx.doi.org/10.1038/ni0610-466 | |
| dc.subject | Catenins | |
| dc.subject | Humans | |
| dc.subject | Immunity, Innate | |
| dc.subject | Interferon Regulatory Factor-3 | |
| dc.subject | Interferon Type I | |
| dc.subject | Listeria monocytogenes | |
| dc.subject | Protein-Serine-Threonine Kinases | |
| dc.subject | RNA-Binding Proteins | |
| dc.subject | Signal Transduction | |
| dc.subject | Vesicular Stomatitis | |
| dc.subject | Immunology and Infectious Disease | |
| dc.title | Catenin' on to nucleic acid sensing | |
| dc.type | Journal Article | |
| dc.source.journaltitle | Nature immunology | |
| dc.source.volume | 11 | |
| dc.source.issue | 6 | |
| dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/infdis_pp/50 | |
| dc.identifier.contextkey | 1901371 | |
| html.description.abstract | <p>Many pathogens induce a type I interferon response via a pathway dependent on the kinase TBK1 and transcription factor IRF3. However, LRRFIP1, a cytosolic sensor of DNA and RNA, triggers interferon production by a β-catenin-dependent signal.</p> | |
| dc.identifier.submissionpath | infdis_pp/50 | |
| dc.contributor.department | Department of Medicine, Division of Infectious Diseases and Immunology | |
| dc.source.pages | 466-8 |