UMass Chan Affiliations
UMass Metabolic NetworkDepartment of Medicine, Division of Cardiovascular Medicine
Document Type
Journal ArticlePublication Date
2017-03-14Keywords
PlateletsThrombosis
Coagulation
Cardiovascular
Bleeding
Biochemistry
Cardiology
Cell Biology
Cellular and Molecular Physiology
Molecular Biology
Metadata
Show full item recordAbstract
Haemostasis and thrombosis are complex, multifactorial processes. There is an evolving understanding of the mechanisms influencing vascular occlusion and the role of inflammation and immunity. Despite major advances in elucidating the mechanistic pathways mediating platelet function and thrombosis, challenges in the treatment of vascular occlusive diseases persist. Pharmacological advances have greatly affected thrombotic outcomes, but this has led to the unwanted side effect of bleeding. Detailed assessment of the impact of non-thrombotic diseases on haemostasis and thrombosis is necessary to better evaluate thrombotic risk and establish optimal treatment. This review will focus on recent advances in understanding the contribution of evolving risk factors to thrombosis.Source
Eur Heart J. 2017 Mar 14;38(11):785-791. doi: 10.1093/eurheartj/ehw550. Link to article on publisher's siteDOI
10.1093/eurheartj/ehw550Permanent Link to this Item
http://hdl.handle.net/20.500.14038/36692PubMed ID
28039338Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1093/eurheartj/ehw550