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dc.contributor.authorHarris, John E.
dc.date2022-08-11T08:09:20.000
dc.date.accessioned2022-08-23T16:27:07Z
dc.date.available2022-08-23T16:27:07Z
dc.date.issued2017-04-01
dc.date.submitted2017-05-25
dc.identifier.citationDermatol Clin. 2017 Apr;35(2):151-161. doi: 10.1016/j.det.2016.11.006. <a href="https://doi.org/10.1016/j.det.2016.11.006">Link to article on publisher's site</a>
dc.identifier.issn0733-8635 (Linking)
dc.identifier.doi10.1016/j.det.2016.11.006
dc.identifier.pmid28317525
dc.identifier.urihttp://hdl.handle.net/20.500.14038/36709
dc.description.abstractChemical-induced depigmentation of the skin has been recognized for more than 75 years, first as an occupational hazard but then extending to those using household commercial products as common as hair dyes. Since their discovery, these chemicals have been used therapeutically in patients with severe vitiligo to depigment their remaining skin and improve their appearance. Because chemical-induced depigmentation is clinically and histologically indistinguishable from nonchemically induced vitiligo, and because these chemicals appear to induce melanocyte autoimmunity, this phenomenon should be known as "chemical-induced vitiligo," rather than less accurate terms that have been previously used.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=28317525&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttps://doi.org/10.1016/j.det.2016.11.006
dc.subjectAutoimmunity
dc.subjectCellular stress
dc.subjectChemical
dc.subjectLeukoderma
dc.subjectMonobenzone
dc.subjectPhenol
dc.subjectRhododendrol
dc.subjectVitiligo
dc.subjectCellular and Molecular Physiology
dc.subjectDermatology
dc.subjectSkin and Connective Tissue Diseases
dc.titleChemical-Induced Vitiligo
dc.typeJournal Article
dc.source.journaltitleDermatologic clinics
dc.source.volume35
dc.source.issue2
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/metnet_pubs/77
dc.identifier.contextkey10212140
html.description.abstract<p>Chemical-induced depigmentation of the skin has been recognized for more than 75 years, first as an occupational hazard but then extending to those using household commercial products as common as hair dyes. Since their discovery, these chemicals have been used therapeutically in patients with severe vitiligo to depigment their remaining skin and improve their appearance. Because chemical-induced depigmentation is clinically and histologically indistinguishable from nonchemically induced vitiligo, and because these chemicals appear to induce melanocyte autoimmunity, this phenomenon should be known as "chemical-induced vitiligo," rather than less accurate terms that have been previously used.</p>
dc.identifier.submissionpathmetnet_pubs/77
dc.contributor.departmentUMass Metabolic Network
dc.contributor.departmentDepartment of Medicine, Division of Dermatology
dc.source.pages151-161


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