UMass Chan AffiliationsMeyers Primary Care Institute
Document TypeJournal Article
Health Services Research
MetadataShow full item record
AbstractHeparin-induced thrombocytopenia (HIT) is an immune-mediated adverse drug reaction to heparin products leading to a prothrombotic state. Devastating clinical sequelae may result, including venous or arterial thromboembolism, limb amputation, and death. Heparin cessation alone is insufficient to manage HIT. Pharmacotherapy with argatroban or lepirudin is essential. This article reviews the pathogenesis, diagnosis, and pharmacotherapy of HIT.
SourceJ Pharm Pract. 2010 Jun;23(3):226-34. Epub 2010 Apr 13. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/37094
Related ResourcesLink to Article in PubMed