Medication Exposure in Pregnancy Risk Evaluation Program: The Prevalence of Asthma Medication Use During Pregnancy
Authors
Hansen, CraigJoski, Peter
Freiman, Heather
Andrade, Susan E.
Toh, Sengwee
Dublin, Sascha
Cheetham, Craig
Cooper, William
Pawloski, Pamala
Li, De-Kun
Beaton, Sarah J.
Kaplan, Sigal
Scott, Pamela E.
Hammad, Tarek
Davis, Robert
UMass Chan Affiliations
Meyers Primary Care InstituteDocument Type
Journal ArticlePublication Date
2012-10-30Keywords
AsthmaAnti-Asthmatic Agents
Pregnancy
Maternal and Child Health
Obstetrics and Gynecology
Pharmaceutical Preparations
Pharmacy and Pharmaceutical Sciences
Respiratory Tract Diseases
Metadata
Show full item recordAbstract
Asthma is one of the most common chronic diseases in women of reproductive age, occurring in up to 8 % of pregnancies. The objective of this study is to assess the prevalence of asthma medication use during pregnancy in a large diverse cohort. We identified women aged 15-45 years who delivered a live born infant between 2001 and 2007 across 11 U.S. health plans within the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). Using health plans' administrative and claims data, and birth certificate data, we identified deliveries for which women filled asthma medications from 90 days before pregnancy through delivery. Prevalence (%) was calculated for asthma diagnosis and medication dispensing. There were 586,276 infants from 575,632 eligible deliveries in the MEPREP cohort. Asthma prevalence among mothers was 6.7 %, increasing from 5.5 % in 2001 to 7.8 % in 2007. A total of 9.7 % (n = 55,914) of women were dispensed asthma medications during pregnancy. The overall prevalence of maintenance-only medication, rescue-only medication, and combined maintenance and rescue medication was 0.6, 6.7, and 2.4 % respectively. The prevalence of maintenance-only use doubled during the study period from 0.4 to 0.8 %, while rescue-only use decreased from 7.4 to 5.8 %. In this large population-based pregnancy cohort, the prevalence of asthma diagnoses increased over time. The dispensing of maintenance-only medication increased over time, while rescue-only medication dispensing decreased over time.Source
Matern Child Health J. 2012 Oct 30. Link to article on publisher's site
DOI
10.1007/s10995-012-1173-xPermanent Link to this Item
http://hdl.handle.net/20.500.14038/37187PubMed ID
23108737Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1007/s10995-012-1173-x