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    Medication Exposure in Pregnancy Risk Evaluation Program: The Prevalence of Asthma Medication Use During Pregnancy

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    Authors
    Hansen, Craig
    Joski, Peter
    Freiman, Heather
    Andrade, Susan E.
    Toh, Sengwee
    Dublin, Sascha
    Cheetham, Craig
    Cooper, William
    Pawloski, Pamala
    Li, De-Kun
    Beaton, Sarah J.
    Kaplan, Sigal
    Scott, Pamela E.
    Hammad, Tarek
    Davis, Robert
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    UMass Chan Affiliations
    Meyers Primary Care Institute
    Document Type
    Journal Article
    Publication Date
    2012-10-30
    Keywords
    Asthma
    Anti-Asthmatic Agents
    Pregnancy
    Maternal and Child Health
    Obstetrics and Gynecology
    Pharmaceutical Preparations
    Pharmacy and Pharmaceutical Sciences
    Respiratory Tract Diseases
    
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    Link to Full Text
    http://dx.doi.org/10.1007/s10995-012-1173-x
    Abstract
    Asthma is one of the most common chronic diseases in women of reproductive age, occurring in up to 8 % of pregnancies. The objective of this study is to assess the prevalence of asthma medication use during pregnancy in a large diverse cohort. We identified women aged 15-45 years who delivered a live born infant between 2001 and 2007 across 11 U.S. health plans within the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). Using health plans' administrative and claims data, and birth certificate data, we identified deliveries for which women filled asthma medications from 90 days before pregnancy through delivery. Prevalence (%) was calculated for asthma diagnosis and medication dispensing. There were 586,276 infants from 575,632 eligible deliveries in the MEPREP cohort. Asthma prevalence among mothers was 6.7 %, increasing from 5.5 % in 2001 to 7.8 % in 2007. A total of 9.7 % (n = 55,914) of women were dispensed asthma medications during pregnancy. The overall prevalence of maintenance-only medication, rescue-only medication, and combined maintenance and rescue medication was 0.6, 6.7, and 2.4 % respectively. The prevalence of maintenance-only use doubled during the study period from 0.4 to 0.8 %, while rescue-only use decreased from 7.4 to 5.8 %. In this large population-based pregnancy cohort, the prevalence of asthma diagnoses increased over time. The dispensing of maintenance-only medication increased over time, while rescue-only medication dispensing decreased over time.
    Source

    Matern Child Health J. 2012 Oct 30. Link to article on publisher's site

    DOI
    10.1007/s10995-012-1173-x
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/37187
    PubMed ID
    23108737
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1007/s10995-012-1173-x
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