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dc.contributor.authorHansen, Craig
dc.contributor.authorJoski, Peter
dc.contributor.authorFreiman, Heather
dc.contributor.authorAndrade, Susan E.
dc.contributor.authorToh, Sengwee
dc.contributor.authorDublin, Sascha
dc.contributor.authorCheetham, Craig
dc.contributor.authorCooper, William
dc.contributor.authorPawloski, Pamala
dc.contributor.authorLi, De-Kun
dc.contributor.authorBeaton, Sarah J.
dc.contributor.authorKaplan, Sigal
dc.contributor.authorScott, Pamela E.
dc.contributor.authorHammad, Tarek
dc.contributor.authorDavis, Robert
dc.date2022-08-11T08:09:23.000
dc.date.accessioned2022-08-23T16:29:11Z
dc.date.available2022-08-23T16:29:11Z
dc.date.issued2012-10-30
dc.date.submitted2013-01-02
dc.identifier.citation<p>Matern Child Health J. 2012 Oct 30. <a href="http://dx.doi.org/10.1007/s10995-012-1173-x" target="_blank">Link to article on publisher's site</a></p>
dc.identifier.issn1092-7875 (Linking)
dc.identifier.doi10.1007/s10995-012-1173-x
dc.identifier.pmid23108737
dc.identifier.urihttp://hdl.handle.net/20.500.14038/37187
dc.description.abstractAsthma is one of the most common chronic diseases in women of reproductive age, occurring in up to 8 % of pregnancies. The objective of this study is to assess the prevalence of asthma medication use during pregnancy in a large diverse cohort. We identified women aged 15-45 years who delivered a live born infant between 2001 and 2007 across 11 U.S. health plans within the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). Using health plans' administrative and claims data, and birth certificate data, we identified deliveries for which women filled asthma medications from 90 days before pregnancy through delivery. Prevalence (%) was calculated for asthma diagnosis and medication dispensing. There were 586,276 infants from 575,632 eligible deliveries in the MEPREP cohort. Asthma prevalence among mothers was 6.7 %, increasing from 5.5 % in 2001 to 7.8 % in 2007. A total of 9.7 % (n = 55,914) of women were dispensed asthma medications during pregnancy. The overall prevalence of maintenance-only medication, rescue-only medication, and combined maintenance and rescue medication was 0.6, 6.7, and 2.4 % respectively. The prevalence of maintenance-only use doubled during the study period from 0.4 to 0.8 %, while rescue-only use decreased from 7.4 to 5.8 %. In this large population-based pregnancy cohort, the prevalence of asthma diagnoses increased over time. The dispensing of maintenance-only medication increased over time, while rescue-only medication dispensing decreased over time.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=23108737&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1007/s10995-012-1173-x
dc.subjectAsthma
dc.subjectAnti-Asthmatic Agents
dc.subjectPregnancy
dc.subjectMaternal and Child Health
dc.subjectObstetrics and Gynecology
dc.subjectPharmaceutical Preparations
dc.subjectPharmacy and Pharmaceutical Sciences
dc.subjectRespiratory Tract Diseases
dc.titleMedication Exposure in Pregnancy Risk Evaluation Program: The Prevalence of Asthma Medication Use During Pregnancy
dc.typeJournal Article
dc.source.journaltitleMaternal and child health journal
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/meyers_pp/598
dc.identifier.contextkey3560201
html.description.abstract<p>Asthma is one of the most common chronic diseases in women of reproductive age, occurring in up to 8 % of pregnancies. The objective of this study is to assess the prevalence of asthma medication use during pregnancy in a large diverse cohort. We identified women aged 15-45 years who delivered a live born infant between 2001 and 2007 across 11 U.S. health plans within the Medication Exposure in Pregnancy Risk Evaluation Program (MEPREP). Using health plans' administrative and claims data, and birth certificate data, we identified deliveries for which women filled asthma medications from 90 days before pregnancy through delivery. Prevalence (%) was calculated for asthma diagnosis and medication dispensing. There were 586,276 infants from 575,632 eligible deliveries in the MEPREP cohort. Asthma prevalence among mothers was 6.7 %, increasing from 5.5 % in 2001 to 7.8 % in 2007. A total of 9.7 % (n = 55,914) of women were dispensed asthma medications during pregnancy. The overall prevalence of maintenance-only medication, rescue-only medication, and combined maintenance and rescue medication was 0.6, 6.7, and 2.4 % respectively. The prevalence of maintenance-only use doubled during the study period from 0.4 to 0.8 %, while rescue-only use decreased from 7.4 to 5.8 %. In this large population-based pregnancy cohort, the prevalence of asthma diagnoses increased over time. The dispensing of maintenance-only medication increased over time, while rescue-only medication dispensing decreased over time.</p>
dc.identifier.submissionpathmeyers_pp/598
dc.contributor.departmentMeyers Primary Care Institute


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