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    Venous thromboembolism in patients with prior stroke

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    Authors
    Piazza, Gregory
    Goldhaber, Samuel Z.
    Kroll-Desrosiers, Aimee R.
    Goldberg, Robert J.
    Emery, Catherine
    Spencer, Frederick A.
    UMass Chan Affiliations
    Department of Quantitative Health Sciences
    Meyers Primary Care Institute
    Document Type
    Journal Article
    Publication Date
    2014-01-01
    Keywords
    Cardiology
    Cardiovascular Diseases
    
    Metadata
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    Link to Full Text
    http://dx.doi.org/10.1177/1076029613487430
    Abstract
    Patients with prior stroke are susceptible to venous thromboembolism (VTE). We studied patients with stroke in the Worcester VTE study of 2488 consecutive patients hospitalized with VTE. In all, 288 (11.6%) had a clinical history of stroke and 2200 (88.4%) did not. Patients with stroke were more likely to die inhospital (9.2% vs 4%) and within 30 days of VTE diagnosis (16.7% vs 6.9%) compared with patients without stroke (all P < .001). Recent immobilization (adjusted odds ratio [OR] 2.15; 95% confidence interval [CI] 1.15-4.09) and inferior vena cava (IVC) filter insertion (adjusted OR 2.1; 95% CI 1.15-3.83) were associated with a doubling of inhospital death. Recent immobilization (adjusted OR 1.84; 95% CI 1.19-2.83) and IVC filter insertion (adjusted OR 1.94; 95% CI 1.2-3.14) were associated with an increased risk of death within 30 days of VTE. In conclusion, patients with VTE and prior stroke were more than twice as likely to die while hospitalized and within 30 days of VTE diagnosis.
    Source
    Clin Appl Thromb Hemost. 2014 Jan;20(1):43-9. doi: 10.1177/1076029613487430. Link to article on publisher's site
    DOI
    10.1177/1076029613487430
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/37293
    PubMed ID
    23637004
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1177/1076029613487430
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