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dc.contributor.authorAwasaki, Takeshi
dc.contributor.authorLee, Tzumin
dc.date2022-08-11T08:09:30.000
dc.date.accessioned2022-08-23T16:33:01Z
dc.date.available2022-08-23T16:33:01Z
dc.date.issued2011-09-01
dc.date.submitted2012-05-24
dc.identifier.citationGlia. 2011 Sep;59(9):1377-86. doi: 10.1002/glia.21133. Epub 2011 Feb 8. <a href="http://dx.doi.org/10.1002/glia.21133">Link to article on publisher's site</a>
dc.identifier.issn0894-1491 (Linking)
dc.identifier.doi10.1002/glia.21133
dc.identifier.pmid21305614
dc.identifier.urihttp://hdl.handle.net/20.500.14038/38006
dc.description.abstractBecause of its genetic, molecular, and behavioral tractability, Drosophila has emerged as a powerful model system for studying molecular and cellular mechanisms underlying the development and function of nervous systems. The Drosophila nervous system has fewer neurons and exhibits a lower glia:neuron ratio than is seen in vertebrate nervous systems. Despite the simplicity of the Drosophila nervous system, glial organization in flies is as sophisticated as it is in vertebrates. Furthermore, fly glial cells play vital roles in neural development and behavior. In addition, powerful genetic tools are continuously being created to explore cell function in vivo. In taking advantage of these features, the fly nervous system serves as an excellent model system to study general aspects of glial cell development and function in vivo. In this article, we review and discuss advanced genetic tools that are potentially useful for understanding glial cell biology in Drosophila. (c) 2011 Wiley-Liss, Inc.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=21305614&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128189/pdf/nihms257905.pdf
dc.subjectCell Biology
dc.subjectDrosophila
dc.subjectMolecular Biology
dc.subjectNeuroglia
dc.subjectNeuroscience and Neurobiology
dc.titleNew tools for the analysis of glial cell biology in Drosophila
dc.typeJournal Article
dc.source.journaltitleGlia
dc.source.volume59
dc.source.issue9
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/neurobiology_pp/4
dc.identifier.contextkey2911119
html.description.abstract<p>Because of its genetic, molecular, and behavioral tractability, Drosophila has emerged as a powerful model system for studying molecular and cellular mechanisms underlying the development and function of nervous systems. The Drosophila nervous system has fewer neurons and exhibits a lower glia:neuron ratio than is seen in vertebrate nervous systems. Despite the simplicity of the Drosophila nervous system, glial organization in flies is as sophisticated as it is in vertebrates. Furthermore, fly glial cells play vital roles in neural development and behavior. In addition, powerful genetic tools are continuously being created to explore cell function in vivo. In taking advantage of these features, the fly nervous system serves as an excellent model system to study general aspects of glial cell development and function in vivo. In this article, we review and discuss advanced genetic tools that are potentially useful for understanding glial cell biology in Drosophila. (c) 2011 Wiley-Liss, Inc.</p>
dc.identifier.submissionpathneurobiology_pp/4
dc.contributor.departmentLee Lab
dc.contributor.departmentNeurobiology
dc.source.pages1377-86


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