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dc.contributor.authorVittimberga, Frank J. Jr.
dc.contributor.authorFoley, David P.
dc.contributor.authorMeyers, William C.
dc.contributor.authorCallery, Mark P.
dc.date2022-08-11T08:09:36.000
dc.date.accessioned2022-08-23T16:37:12Z
dc.date.available2022-08-23T16:37:12Z
dc.date.issued1998-04-04
dc.date.submitted2008-02-29
dc.identifier.citationAnn Surg. 1998 Mar;227(3):326-34.
dc.identifier.issn0003-4932 (Print)
dc.identifier.pmid9527054
dc.identifier.urihttp://hdl.handle.net/20.500.14038/38960
dc.description.abstractOBJECTIVE: The authors review studies relating to the immune responses evoked by laparoscopic surgery. SUMMARY BACKGROUND DATA: Laparoscopic surgery has gained rapid acceptance based on clinical grounds. Patients benefit from faster recovery, decreased pain, and quicker return to normal activities. Only more recently have attempts been made to identify the metabolic and immune responses that may underlie this clinical success. The immune responses to laparoscopy are now being evaluated in relation to the present knowledge of immune responses to traditional laparotomy and surgery in general. METHODS: A review of the published literature of the immune and metabolic responses to laparoscopy was performed. Laparoscopic surgery is compared with the traditional laparotomy on the basis of local and systemic immune responses and patterns of tumor growth. The impact of pneumoperitoneum and insufflation gases on the immune response is also reviewed. CONCLUSIONS: The systemic immune responses for surgery in general may not apply to laparoscopic surgery. The body's response to laparoscopy is one of lesser immune activation as opposed to immunosuppression.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9527054&dopt=Abstract ">Link to article in PubMed</a>
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1191269/pdf/annsurg00013-0024.pdf
dc.subjectCarbon Dioxide
dc.subjectHumans
dc.subject*Immunity
dc.subjectInterleukin-6
dc.subject*Laparoscopy
dc.subjectLeukocyte Count
dc.subjectMacrophage Activation
dc.subjectNeoplasms
dc.subjectPeritoneum
dc.subjectPneumoperitoneum, Artificial
dc.subjectLife Sciences
dc.subjectMedicine and Health Sciences
dc.titleLaparoscopic surgery and the systemic immune response
dc.typeArticle
dc.source.journaltitleAnnals of surgery
dc.source.volume227
dc.source.issue3
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/oapubs/179
dc.identifier.contextkey441944
html.description.abstract<p>OBJECTIVE: The authors review studies relating to the immune responses evoked by laparoscopic surgery. SUMMARY BACKGROUND DATA: Laparoscopic surgery has gained rapid acceptance based on clinical grounds. Patients benefit from faster recovery, decreased pain, and quicker return to normal activities. Only more recently have attempts been made to identify the metabolic and immune responses that may underlie this clinical success. The immune responses to laparoscopy are now being evaluated in relation to the present knowledge of immune responses to traditional laparotomy and surgery in general. METHODS: A review of the published literature of the immune and metabolic responses to laparoscopy was performed. Laparoscopic surgery is compared with the traditional laparotomy on the basis of local and systemic immune responses and patterns of tumor growth. The impact of pneumoperitoneum and insufflation gases on the immune response is also reviewed. CONCLUSIONS: The systemic immune responses for surgery in general may not apply to laparoscopic surgery. The body's response to laparoscopy is one of lesser immune activation as opposed to immunosuppression.</p>
dc.identifier.submissionpathoapubs/179
dc.contributor.departmentDepartment of Surgery
dc.source.pages326-34


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