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    A 30-year perspective (1975-2005) into the changing landscape of patients hospitalized with initial acute myocardial infarction: Worcester Heart Attack Study

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    Authors
    Floyd, Kevin C.
    Yarzebski, Jorge L.
    Spencer, Frederick A.
    Lessard, Darleen M.
    Dalen, James E.
    Alpert, Joseph S.
    Gore, Joel M.
    Goldberg, Robert J.
    UMass Chan Affiliations
    Department of Medicine, Division of Cardiovascular Medicine
    Document Type
    Journal Article
    Publication Date
    2009-12-25
    Keywords
    Academic Medical Centers
    Age Distribution
    Aged
    Cardiovascular Agents
    Comorbidity
    Coronary Artery Bypass
    Female
    Hospital Mortality
    Hospitalization
    Humans
    Incidence
    Male
    Massachusetts
    Middle Aged
    Myocardial Infarction
    Population Surveillance
    Prevalence
    Sex Distribution
    Thrombolytic Therapy
    Life Sciences
    Medicine and Health Sciences
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    Link to Full Text
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776766/
    Abstract
    BACKGROUND: The effects of lifestyle changes and evolving treatment practices on coronary disease incidence rates, demographic and clinical profile, and the short-term outcomes of patients hospitalized with acute myocardial infarction have not been well characterized. The purpose of this study was to examine multidecade-long trends (1975-2005) in the incidence rates, demographic and clinical characteristics, treatment practices, and hospital outcomes of patients hospitalized with an initial acute myocardial infarction from a population-based perspective. METHODS AND RESULTS: Residents of the Worcester, Mass, metropolitan area (median age, 37 years; 89% white) hospitalized with an initial acute myocardial infarction (n=8898) at all greater-Worcester medical centers during 15 annual periods between 1975 and 2005 comprised the sample of interest. The incidence rates of initial acute myocardial infarction were lower in 2005 (209 of 100,000 population) than in 1975 (277 of 100,000), although these trends varied inconsistently over time. Patients hospitalized during the most recent study years were significantly older (mean age, 64 years in 1975; 71 years in 2005), more likely to be women (38% in 1975; 48% in 2005), and have a greater prevalence of comorbidities. Hospitalized patients were increasingly more likely to receive effective cardiac medications and coronary interventional procedures for the period under investigation. Hospital survival rates improved significantly over time (81% survived in 1975; 91% survived in 2005), although varying trends were observed in the occurrence of clinically important complications. CONCLUSIONS: The results of this community-wide investigation provide insight into the changing magnitude, characteristics, management practices, and outcomes of patients hospitalized with a first myocardial infarction.
    Source

    Circ Cardiovasc Qual Outcomes. 2009 Mar;2(2):88-95. Epub 2009 Mar 5. Link to article on publisher's site

    DOI
    10.1161/CIRCOUTCOMES.108.811828
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/39319
    PubMed ID
    20031820
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    Link to Article in PubMed

    ae974a485f413a2113503eed53cd6c53
    10.1161/CIRCOUTCOMES.108.811828
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