Vibrotactile stimulation: A non-pharmacological intervention for opioid-exposed newborns
Barton, Bruce A.
Salisbury, Elisabeth B.
UMass Chan AffiliationsDepartment of Pediatrics
Department of Quantitative Health Sciences
Department of Neurology
Document TypeJournal Article
Keywordsstochastic vibrotactile stimulation
neonatal drug withdrawal
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Maternal and Child Health
Substance Abuse and Addiction
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AbstractOBJECTIVE: To examine the therapeutic potential of stochastic vibrotactile stimulation (SVS) as a complementary non-pharmacological intervention for withdrawal in opioid-exposed newborns. STUDY DESIGN: A prospective, within-subjects single-center study was conducted in 26 opioid-exposed newborns ( > 37 weeks; 16 male) hospitalized since birth and treated pharmacologically for Neonatal Abstinence Syndrome. A specially-constructed mattress delivered low-level SVS (30-60Hz, 10-12mum RMS), alternated in 30-min intervals between continuous vibration (ON) and no vibration (OFF) over a 6-8 hr session. Movement activity, heart rate, respiratory rate, axillary temperature and blood-oxygen saturation were calculated separately for ON and OFF. RESULTS: There was a 35% reduction in movement activity with SVS (p<0.001), with significantly fewer movement periods > 30 sec duration for ON than OFF (p = 0.003). Incidents of tachypneic breaths and tachycardic heart beats were each significantly reduced with SVS, whereas incidents of eupneic breaths and eucardic heart beats each significantly increased with SVS (p<0.03). Infants maintained body temperature and arterial-blood oxygen level independent of stimulation condition. CONCLUSIONS: SVS reduced hyperirritability and pathophysiological instabilities commonly observed in pharmacologically-managed opioid-exposed newborns. SVS may provide an effective complementary therapeutic intervention for improving autonomic function in newborns with Neonatal Abstinence Syndrome.
SourcePLoS One. 2017 Apr 20;12(4):e0175981. eCollection 2017. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/40252
Related ResourcesLink to Article in PubMed
RightsCopyright © 2017 Zuzarte et al.