Vibrotactile stimulation: A non-pharmacological intervention for opioid-exposed newborns
Authors
Zuzarte, IanIndic, Premananda
Barton, Bruce A.
Paydarfar, David
Bednarek, Francis
Salisbury, Elisabeth B.
UMass Chan Affiliations
Department of PediatricsDepartment of Quantitative Health Sciences
Department of Neurology
Document Type
Journal ArticlePublication Date
2017-04-20Keywords
stochastic vibrotactile stimulationopioid-exposed newborns
neonatal drug withdrawal
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Maternal and Child Health
Neurology
Pediatrics
Substance Abuse and Addiction
Metadata
Show full item recordAbstract
OBJECTIVE: To examine the therapeutic potential of stochastic vibrotactile stimulation (SVS) as a complementary non-pharmacological intervention for withdrawal in opioid-exposed newborns. STUDY DESIGN: A prospective, within-subjects single-center study was conducted in 26 opioid-exposed newborns ( > 37 weeks; 16 male) hospitalized since birth and treated pharmacologically for Neonatal Abstinence Syndrome. A specially-constructed mattress delivered low-level SVS (30-60Hz, 10-12mum RMS), alternated in 30-min intervals between continuous vibration (ON) and no vibration (OFF) over a 6-8 hr session. Movement activity, heart rate, respiratory rate, axillary temperature and blood-oxygen saturation were calculated separately for ON and OFF. RESULTS: There was a 35% reduction in movement activity with SVS (p<0.001), with significantly fewer movement periods > 30 sec duration for ON than OFF (p = 0.003). Incidents of tachypneic breaths and tachycardic heart beats were each significantly reduced with SVS, whereas incidents of eupneic breaths and eucardic heart beats each significantly increased with SVS (p<0.03). Infants maintained body temperature and arterial-blood oxygen level independent of stimulation condition. CONCLUSIONS: SVS reduced hyperirritability and pathophysiological instabilities commonly observed in pharmacologically-managed opioid-exposed newborns. SVS may provide an effective complementary therapeutic intervention for improving autonomic function in newborns with Neonatal Abstinence Syndrome.Source
PLoS One. 2017 Apr 20;12(4):e0175981. eCollection 2017. Link to article on publisher's siteDOI
10.1371/journal.pone.0175981Permanent Link to this Item
http://hdl.handle.net/20.500.14038/40252PubMed ID
28426726Related Resources
Link to Article in PubMedRights
Copyright © 2017 Zuzarte et al.Distribution License
http://creativecommons.org/licenses/by/4.0/ae974a485f413a2113503eed53cd6c53
10.1371/journal.pone.0175981