Cardioprotection with adenosine: 'a riddle wrapped in a mystery'
| dc.contributor.author | Przyklenk, Karin | |
| dc.contributor.author | Whittaker, Peter | |
| dc.date | 2022-08-11T08:09:48.000 | |
| dc.date.accessioned | 2022-08-23T16:44:06Z | |
| dc.date.available | 2022-08-23T16:44:06Z | |
| dc.date.issued | 2005-05-17 | |
| dc.date.submitted | 2008-04-14 | |
| dc.identifier.citation | <p>Br J Pharmacol. 2005 Jul;145(6):699-700. <a href="http://dx.doi.org/10.1038/sj.bjp.0706261 ">Link to article on publisher's site</a></p> | |
| dc.identifier.issn | 0007-1188 (Print) | |
| dc.identifier.doi | 10.1038/sj.bjp.0706261 | |
| dc.identifier.pmid | 15895103 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.14038/40434 | |
| dc.description.abstract | Review of the published literature on adenosine and cardioprotection could lead one to paraphrase the famous words of Sir Winston Churchill (Radio broadcast, 1 October 1939 (in reference to Russia)) and conclude: 'I cannot forecast to you the action of adenosine. It is a riddle wrapped in a mystery inside an enigma'. That is, although it is well-established that adenosine can render cardiomyocytes resistant to lethal ischemia/reperfusion-induced injury, new and intriguing insights continue to emerge as to the mechanisms by which adenosine might limit myocardial infarct size. | |
| dc.language.iso | en_US | |
| dc.relation | <p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15895103&dopt=Abstract ">Link to article in PubMed</a></p> | |
| dc.relation.url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1576201/ | |
| dc.subject | Adenosine | |
| dc.subject | Animals | |
| dc.subject | Cardiotonic Agents | |
| dc.subject | Myocardial Infarction | |
| dc.subject | Myocardial Reperfusion Injury | |
| dc.subject | Nitric Oxide | |
| dc.subject | Nitric Oxide Synthase | |
| dc.subject | Rats | |
| dc.subject | Life Sciences | |
| dc.subject | Medicine and Health Sciences | |
| dc.title | Cardioprotection with adenosine: 'a riddle wrapped in a mystery' | |
| dc.type | Journal Article | |
| dc.source.journaltitle | British journal of pharmacology | |
| dc.source.volume | 145 | |
| dc.source.issue | 6 | |
| dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/oapubs/324 | |
| dc.identifier.contextkey | 489662 | |
| html.description.abstract | <p>Review of the published literature on adenosine and cardioprotection could lead one to paraphrase the famous words of Sir Winston Churchill (Radio broadcast, 1 October 1939 (in reference to Russia)) and conclude: 'I cannot forecast to you the action of adenosine. It is a riddle wrapped in a mystery inside an enigma'. That is, although it is well-established that adenosine can render cardiomyocytes resistant to lethal ischemia/reperfusion-induced injury, new and intriguing insights continue to emerge as to the mechanisms by which adenosine might limit myocardial infarct size.</p> | |
| dc.identifier.submissionpath | oapubs/324 | |
| dc.contributor.department | Department of Anesthesiology | |
| dc.contributor.department | Department of Emergency Medicine | |
| dc.source.pages | 699-700 |